Adderall and Tolterodine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Tolterodine (tolterodine tartrate). Common drug interactions include cholelithiasis among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Tolterodine. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Tolterodine?

Tolterodine has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 8,156 Tolterodine users. Check the latest studies of Tolterodine.

On Jul, 12, 2026

87 people who take Adderall and Tolterodine together, and have interactions are studied.

Adderall and Tolterodine drug interactions.

What are the common drug interactions of Adderall and Tolterodine, by gender? *:

female:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cough
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Dyspepsia (indigestion)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastritis (inflammation of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypersomnia (excessive daytime sleepiness (eds))

male:

Anxiety
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Renal failure (kidney dysfunction)
Bladder obstruction
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Eye haemorrhage (bleeding in the eye)
Nasopharyngitis (inflammation of the nasopharynx)
Osteonecrosis (death of bone)

What are the common drug interactions of Adderall and Tolterodine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Visual impairment
Balance disorder
Fall
Lower limb fracture

30-39:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Abscess (pus)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Asthma
Balance disorder
Bruxism (habitual grinding of the teeth, typically during sleep)
Constipation
Dehydration (dryness resulting from the removal of water)

40-49:

Anxiety
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Emotional distress
Hip fracture
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Upper respiratory tract infection
Abnormal behaviour
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

50-59:

Gait disturbance
Gingival bleeding (bleeding gums)
Hypertension (high blood pressure)
Hyperthyroidism (over activity of the thyroid gland)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Loss of consciousness
Muscle tightness
Pain

60+:

Disability
Myalgia (muscle pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depressed mood
Dizziness
Eye haemorrhage (bleeding in the eye)
Face oedema (swelling of face)
Fatigue (feeling of tiredness)
Gait disturbance
Generalised oedema (swelling all over the body)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 42 people, 48.28%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 19 people, 21.84%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 19 people, 21.84%
Drowsiness: 8 people, 9.20%
High Blood Pressure: 7 people, 8.05%
Depression: 7 people, 8.05%
Neuralgia (pain in one or more nerves): 6 people, 6.90%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 6.90%
High Blood Cholesterol: 6 people, 6.90%
Stress And Anxiety: 5 people, 5.75%

* Approximation only. Some reports may have incomplete information.

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