Adriamycin pfs and Aciphex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adriamycin pfs (doxorubicin hydrochloride) and Aciphex (rabeprazole sodium). Common drug interactions include gingival ulceration among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Adriamycin pfs and Aciphex. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Adriamycin pfs?

Adriamycin pfs has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 6,495 Adriamycin pfs users. Check the latest studies of Adriamycin pfs.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.



On Jul, 28, 2026

27 people who take Adriamycin pfs and Aciphex together, and have interactions are studied.

Adriamycin pfs and Aciphex drug interactions.

What are the common drug interactions of Adriamycin Pfs and Aciphex, by gender? *:

female:

  1. Gingival ulceration (ulcer on gums)
  2. Gingivitis (inflammation of gums)
  3. Herpes zoster
  4. Hypertension (high blood pressure)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  7. Jaw fracture
  8. Macroglossia (large tongue)
  9. Mass
  10. Mitral valve calcification (calcium deposit in mitral valve)

male:

  1. Anxiety
  2. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  3. Nausea (feeling of having an urge to vomit)
  4. Pain
  5. Pneumonia
  6. Visual field defect
  7. Apnoea (suspension of external breathing)
  8. Bruxism (habitual grinding of the teeth, typically during sleep)
  9. Hypopnoea (decrease in the breathing rate)
  10. Snoring

What are the common drug interactions of Adriamycin Pfs and Aciphex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Muscle cramp (painful sensation caused by muscle contraction)

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Colitis (inflammation of colon)
  3. Dehydration (dryness resulting from the removal of water)
  4. Diarrhoea
  5. Gastroenteritis (inflammation of stomach and intestine)
  6. Nausea (feeling of having an urge to vomit)
  7. Vomiting

50-59:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Activities of daily living impaired
  3. Altered visual depth perception
  4. Anaemia (lack of blood)
  5. Back pain
  6. Bacterial test positive
  7. Blood alkaline phosphatase increased
  8. Blood calcium increased
  9. Bone disorder
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

  1. Anxiety
  2. Cataract (clouding of the lens inside the eye)
  3. Confusional state
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Abscess jaw (tooth abscess or root abscess)
  6. Activities of daily living impaired
  7. Anaemia (lack of blood)
  8. Asthenia (weakness)
  9. Asthma
  10. Back disorder

What are the existing conditions these people have? *

  1. Pain: 10 people, 37.04%
  2. Metastases To Bone (cancer spreads to bone): 10 people, 37.04%
  3. Breast Cancer Metastatic: 5 people, 18.52%
  4. Pain In Jaw: 2 people, 7.41%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.41%
  6. Breast Cancer: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Adriamycin pfs and Aciphex?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adriamycin pfs and Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adriamycin pfs:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adriamycin pfs and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aciphex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxorubicin hydrochloride and rabeprazole sodium (the active ingredients of Adriamycin pfs and Aciphex, respectively), and Adriamycin pfs and Aciphex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: