Advil and Brilinta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advil (ibuprofen) and Brilinta (ticagrelor). Common drug interactions include abdominal pain upper among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Advil and Brilinta. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

What is Brilinta?

Brilinta has active ingredients of ticagrelor. It is often used in stent. eHealthMe is studying from 22,469 Brilinta users. Check the latest studies of Brilinta.



On Jul, 16, 2026

23 people who take Advil and Brilinta together, and have interactions are studied.

Advil and Brilinta drug interactions.

What are the common drug interactions of Advil and Brilinta, by gender? *:

female:

  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Back pain
  4. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Dehydration (dryness resulting from the removal of water)
  7. Diarrhoea
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hypersensitivity
  10. Nasopharyngitis (inflammation of the nasopharynx)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Constipation
  4. Cough
  5. Haematochezia (passage of stools containing blood)
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Pain in extremity
  8. Pruritus (severe itching of the skin)
  9. Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
  10. Tooth abscess (pus formation in tooth)

What are the common drug interactions of Advil and Brilinta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  2. Cardiac failure congestive
  3. Chronic kidney disease
  4. Diabetic nephropathy (diabetic kidney disease)
  5. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  6. Hypertensive heart disease
  7. Nephropathy (damage to or disease of a kidney)
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Renal injury (kidney injury)

40-49:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

  1. Arthralgia (joint pain)
  2. Constipation
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Cough
  5. Haematochezia (passage of stools containing blood)
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Pain in extremity
  8. Pruritus (severe itching of the skin)
  9. Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
  10. Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

  1. Fatigue (feeling of tiredness)
  2. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  3. Dyspnoea (difficult or laboured respiration)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Weight increased
  7. White blood cell count increased
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Hot flush (sudden feelings of heat)
  10. Neck pain

What are the existing conditions these people have? *

  1. Heart Attack: 6 people, 26.09%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 17.39%
  3. High Blood Cholesterol: 4 people, 17.39%
  4. Type 2 Diabetes: 2 people, 8.70%
  5. Tooth Disorder (tooth disease): 2 people, 8.70%
  6. Stress And Anxiety: 2 people, 8.70%
  7. Prostate Cancer: 2 people, 8.70%
  8. High Blood Pressure: 2 people, 8.70%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
  10. Diabetes: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Advil and Brilinta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Brilinta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Brilinta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and ticagrelor (the active ingredients of Advil and Brilinta, respectively), and Advil and Brilinta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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