Advil and Loprox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Advil (ibuprofen) and Loprox (ciclopirox). Common drug interactions include dyspnoea among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Advil and Loprox. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

What is Loprox?

Loprox has active ingredients of ciclopirox. eHealthMe is studying from 618 Loprox users. Check the latest studies of Loprox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

18 people who take Advil and Loprox together, and have interactions are studied.

Advil and Loprox drug interactions.

What are the common drug interactions of Advil and Loprox, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anaemia (lack of blood)
  3. Conjunctivitis viral (infection of conjunctiva by virus)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Gastritis (inflammation of stomach)
  6. Herpes zoster
  7. Insomnia (sleeplessness)
  8. Lung neoplasm (tumour of lung)
  9. Panic attack
  10. Pericardial effusion (fluid around the heart)

male:

  1. Asthenia (weakness)
  2. Ataxia (loss of full control of bodily movements)
  3. Cerebrovascular insufficiency (insufficient blood supply to brain)
  4. Fall
  5. Lumbar radiculopathy (radicular pain in the low back and legs)
  6. Urinary tract infection

What are the common drug interactions of Advil and Loprox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Food poisoning (poison in food)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hand fracture
  4. Head injury
  5. Hepatomegaly (abnormal enlargement of the liver)
  6. Herpes simplex (herpes simplex is a common viral infection)
  7. Hodgkin's disease (cancer originating from white blood cells)
  8. Laryngocele (a congenital anomalous air sac communicating with the cavity of the larynx)
  9. Myalgia (muscle pain)
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

30-39:

n/a

40-49:

  1. Rash
  2. Arthralgia (joint pain)
  3. Back pain
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Gait disturbance
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Joint effusion (presence of extra fluid in joint covering)
  9. Joint warmth
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

50-59:

  1. Chest discomfort
  2. Depression
  3. Dermal cyst
  4. Dizziness
  5. Ear infection
  6. Ear pain
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  9. Haematochezia (passage of stools containing blood)
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus)

60+:

  1. Asthenia (weakness)
  2. Ataxia (loss of full control of bodily movements)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Lumbar radiculopathy (radicular pain in the low back and legs)
  7. Urinary tract infection

What are the existing conditions these people have? *

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 7 people, 38.89%
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 27.78%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.11%
  4. Bladder Cancer: 2 people, 11.11%
  5. Pain In Extremity: 1 person, 5.56%
  6. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
  8. Infection: 1 person, 5.56%
  9. Hypokalemia (low potassium): 1 person, 5.56%
  10. High Blood Pressure: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and Loprox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Advil and Loprox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Loprox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loprox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and ciclopirox (the active ingredients of Advil and Loprox, respectively), and Advil and Loprox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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