Afinitor and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Afinitor (everolimus) and Cefazolin (cefazolin sodium). Common drug interactions include cardiomegaly among females and c-reactive protein increased among males.

The phase IV clinical study analyzes what interactions people have when they take Afinitor and Cefazolin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

On Aug, 03, 2026

22 people who take Afinitor and Cefazolin together, and have interactions are studied.

Afinitor and Cefazolin drug interactions.

What are the common drug interactions of Afinitor and Cefazolin, by gender? *:

female:

Cardiomegaly (increased size of heart than normal)
Coarctation of the aorta (narrowing of the part of aorta)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Head injury
Oedema (fluid collection in tissue)
Pericardial effusion (fluid around the heart)
Pulmonary valve incompetence
Syncope (loss of consciousness with an inability to maintain postural tone)
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
Weight increased

male:

C-reactive protein increased
Pleural effusion (water on the lungs)
Renal impairment (severely reduced kidney function)
Dyspnoea (difficult or laboured respiration)
Cardiac failure congestive
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
General physical health deterioration (weak health status)
Haemoglobin decreased
Metastases to bone (cancer spreads to bone)
Neoplasm malignant (cancer tumour)

What are the common drug interactions of Afinitor and Cefazolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Pleural effusion (water on the lungs)
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Blood potassium decreased
C-reactive protein increased
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)

50-59:

C-reactive protein increased
Pneumonia bacterial (pneumonia associated with bacterial infection)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Myocarditis (inflammation of heart muscle myocardium)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Cellulitis (infection under the skin)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Malignant neoplasm progression (cancer tumour came back)

60+:

C-reactive protein increased
Epistaxis (bleed from the nose)
Renal impairment (severely reduced kidney function)
General physical health deterioration (weak health status)
Haemoglobin decreased
Neoplasm progression (growth of tumour)
Cough
Liver disorder (liver diseases)
Oedema peripheral (superficial swelling)
Catheter site infection (infection at the site of insertion)

What are the existing conditions these people have? *

Constipation: 9 people, 40.91%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 8 people, 36.36%
Pressure Ulcer: 7 people, 31.82%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 7 people, 31.82%
Pain: 7 people, 31.82%
High Blood Pressure: 7 people, 31.82%
Dermatosis (a disease of the skin, esp. one that does not cause inflammation): 7 people, 31.82%
Breast Cancer: 4 people, 18.18%
Hypokalemia (low potassium): 2 people, 9.09%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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