Aggrenox and Hctz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aggrenox (aspirin; dipyridamole) and Hctz (hydrochlorothiazide). Common drug interactions include fall among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aggrenox and Hctz. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Aggrenox?

Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

On Jul, 17, 2026

34 people who take Aggrenox and Hctz together, and have interactions are studied.

What are the common drug interactions of Aggrenox and Hctz, by gender? *:

female:

Fall
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Heart rate decreased
Hip fracture
Muscle spasms (muscle contraction)
Pruritus (severe itching of the skin)
Renal failure acute (rapid kidney dysfunction)

male:

Chronic kidney disease
Rash
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Platelet count decreased

What are the common drug interactions of Aggrenox and Hctz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Chest pain
Dyspnoea (difficult or laboured respiration)
Fall
Headache (pain in head)
Hip fracture
Hyperhidrosis (abnormally increased sweating)
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

60+:

Fall
Diarrhoea
Renal failure acute (rapid kidney dysfunction)
Respiratory disorder (respiratory disease)
Visual acuity reduced (reduced clearness of vision)
Blood calcium increased
Headache (pain in head)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

High Blood Cholesterol: 8 people, 23.53%
Diabetes: 6 people, 17.65%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.71%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.82%
Type 2 Diabetes: 2 people, 5.88%
Stress And Anxiety: 2 people, 5.88%
Pain: 2 people, 5.88%
Osteoporosis (bones weak and more likely to break): 2 people, 5.88%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.88%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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