Aimovig and Estrace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aimovig (erenumab-aooe) and Estrace (estradiol). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Aimovig and Estrace. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Aimovig?

Aimovig has active ingredients of erenumab-aooe. eHealthMe is studying from 49,930 Aimovig users. Check the latest studies of Aimovig.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.



On Aug, 11, 2026

32 people who take Aimovig and Estrace together, and have interactions are studied.

Aimovig and Estrace drug interactions.

What are the common drug interactions of Aimovig and Estrace, by gender? *:

female:

  1. Migraine (headache)
  2. Infusion related reaction
  3. Colonoscopy
  4. Dehydration (dryness resulting from the removal of water)
  5. Fatigue (feeling of tiredness)
  6. Fungal infection
  7. Immunoglobulins decreased
  8. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  9. Insomnia (sleeplessness)
  10. Nasopharyngitis (inflammation of the nasopharynx)

male:

n/a

What are the common drug interactions of Aimovig and Estrace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal discomfort
  2. Diarrhoea
  3. Hypotension (abnormally low blood pressure)
  4. Nausea (feeling of having an urge to vomit)
  5. Retching (strong involuntary effort to vomit)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

  1. Arthralgia (joint pain)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Cystitis (inflammation of the wall of the bladder)
  4. Dizziness
  5. Heart rate increased
  6. Hypertension (high blood pressure)
  7. Influenza
  8. Injection site scar
  9. Kidney infection
  10. Myalgia (muscle pain)

50-59:

  1. Constipation
  2. Decreased appetite
  3. Disturbance in attention
  4. Fatigue (feeling of tiredness)
  5. Impaired driving ability
  6. Influenza like illness
  7. Intestinal perforation (complete penetration of the wall of the intestine)
  8. Large intestine perforation (hole in large intestine)
  9. Visual impairment
  10. Wrist fracture

60+:

  1. Oropharyngeal pain
  2. Pain
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Bedridden
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Cough
  7. Cystitis (inflammation of the wall of the bladder)
  8. Dental caries
  9. Dizziness
  10. Dysuria (painful or difficult urination)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 15 people, 46.88%
  2. Migraine (headache): 8 people, 25.00%
  3. Primary Immunodeficiency Syndrome: 5 people, 15.62%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 12.50%
  5. Headache (pain in head): 3 people, 9.38%
  6. Urinary Tract Infection Pseudomonal: 2 people, 6.25%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.25%
  8. Depression: 2 people, 6.25%
  9. Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 2 people, 6.25%
  10. Escherichia Urinary Tract Infection (urinary tract infection by escherichia coli): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Aimovig and Estrace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aimovig and Estrace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aimovig:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Estrace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aimovig and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estrace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on erenumab-aooe and estradiol (the active ingredients of Aimovig and Estrace, respectively), and Aimovig and Estrace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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