Naltrexone and Aimovig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naltrexone (naltrexone) and Aimovig (erenumab-aooe). Common drug interactions include sinusitis among females.

The phase IV clinical study analyzes what interactions people have when they take Naltrexone and Aimovig. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,828 Naltrexone users. Check the latest studies of Naltrexone.

What is Aimovig?

Aimovig has active ingredients of erenumab-aooe. eHealthMe is studying from 49,929 Aimovig users. Check the latest studies of Aimovig.



On Jan, 10, 2026

40 people who take Naltrexone and Aimovig together, and have interactions are studied.

Naltrexone and Aimovig drug interactions.

What are the common drug interactions of Naltrexone and Aimovig, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Fatigue (feeling of tiredness)
  3. Upper respiratory tract infection
  4. Urinary tract infection
  5. Constipation
  6. Nephrolithiasis (calculi in the kidneys)
  7. Surgery
  8. Infusion related reaction
  9. Anxiety
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

n/a

What are the common drug interactions of Naltrexone and Aimovig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Infusion related reaction
  4. Pain
  5. Pruritus (severe itching of the skin)
  6. Tenderness (pain or discomfort when an affected area is touched)
  7. Weight increased
  8. Constipation

40-49:

  1. Abscess (pus)
  2. Bacterial infection
  3. Dactylitis (dactylitis or sausage digit is inflammation of an entire digit (a finger or toe), and can be painful)
  4. Gastrointestinal ulcer
  5. Infection
  6. Influenza
  7. Sinusitis (inflammation of sinus)
  8. Upper respiratory tract infection
  9. Urinary tract infection
  10. Cough

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Weight decreased
  3. Constipation
  4. Abdominal distension
  5. Abdominal pain
  6. Gastrointestinal pain
  7. Hypophagia (reduced food intake)
  8. Mobility decreased (ability to move is reduced)

60+:

  1. Drug hypersensitivity
  2. Food allergy
  3. Neuropathy peripheral (surface nerve damage)
  4. Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 32.50%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 20.00%
  3. Immunodeficiency Common Variable: 6 people, 15.00%
  4. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 6 people, 15.00%
  5. Migraine (headache): 3 people, 7.50%
  6. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 5.00%
  7. Primary Immunodeficiency Syndrome: 2 people, 5.00%
  8. Inflammation: 2 people, 5.00%
  9. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 5.00%
  10. Food Allergy: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naltrexone and Aimovig:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aimovig:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aimovig and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naltrexone and erenumab-aooe (the active ingredients of Naltrexone and Aimovig, respectively), and Naltrexone and Aimovig (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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