Akynzeo and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Akynzeo (netupitant; palonosetron hydrochloride) and Cefazolin (cefazolin sodium). Common drug interactions include febrile neutropenia among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Akynzeo and Cefazolin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Akynzeo?

Akynzeo has active ingredients of netupitant; palonosetron hydrochloride. eHealthMe is studying from 1,332 Akynzeo users. Check the latest studies of Akynzeo.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

11 people who take Akynzeo and Cefazolin together, and have interactions are studied.

Akynzeo and Cefazolin drug interactions.

What are the common drug interactions of Akynzeo and Cefazolin, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Alopecia (absence of hair from areas of the body)
Blood bilirubin increased
Blood lactate dehydrogenase increased
Chest discomfort
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
White blood cell count decreased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Thrombocytopenia (decrease of platelets in blood)
Death
Hypertension (high blood pressure)
Radiation pneumonitis (inflammation of lung due to radiation)
Anaemia (lack of blood)
General physical health deterioration (weak health status)

What are the common drug interactions of Akynzeo and Cefazolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)

50-59:

Blood lactate dehydrogenase increased
Chest discomfort
Death
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Oedema peripheral (superficial swelling)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Anaemia (lack of blood)
General physical health deterioration (weak health status)
Neutropenia (an abnormally low number of neutrophils)
White blood cell count decreased

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 5 people, 45.45%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 45.45%
Urinary Tract Infection: 3 people, 27.27%
Pain In Extremity: 3 people, 27.27%
Device Related Infection: 3 people, 27.27%
Neuropathy Peripheral (surface nerve damage): 3 people, 27.27%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 27.27%
Headache (pain in head): 3 people, 27.27%
Generalised Oedema (swelling all over the body): 3 people, 27.27%
Stress And Anxiety: 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

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