Alavert and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alavert (loratadine) and Profen (ibuprofen). Common drug interactions include osteonecrosis of jaw among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Alavert and Profen. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Alavert?

Alavert has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 2,062 Alavert users. Check the latest studies of Alavert.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 09, 2026

71 people who take Alavert and Profen together, and have interactions are studied.

What are the common drug interactions of Alavert and Profen, by gender? *:

female:

Osteonecrosis of jaw (death of bone of jaw)
Post lumbar puncture syndrome
Pulmonary embolism (blockage of the main artery of the lung)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Spinal osteoarthritis (joint cartilage loss in spine)
Vision blurred
Crying
Nausea (feeling of having an urge to vomit)
Dizziness
Pharyngitis (inflammation of the pharynx, causing a sore throat)

male:

Chronic kidney disease
Abnormal dreams
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Disease recurrence
Dizziness
Dyspepsia (indigestion)
Gingival bleeding (bleeding gums)
Haemorrhage urinary tract (bleeding from uterine)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)

What are the common drug interactions of Alavert and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cholecystitis chronic (long lasting infection of gallbladder)
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Injury
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)

20-29:

Chronic kidney disease
Renal failure (kidney dysfunction)

30-39:

Abdominal pain upper
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Body temperature increased
Chest pain
Diarrhoea
Dizziness
Dysarthria (speech disorder)
Headache (pain in head)
Oropharyngeal pain

40-49:

Injection site bruising
Injection site mass
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Angioedema (rapid swelling of the dermis)
Dehydration (dryness resulting from the removal of water)
Flushing (the warm, red condition of human skin)
Hot flush (sudden feelings of heat)
Hypokinesia (decreased bodily movement)

50-59:

Tri-iodothyronine decreased
Upper respiratory tract infection
Uterine prolapse
Visual acuity reduced (reduced clearness of vision)
Weight increased
Bone deformity
Cardiovascular disorder (heart diseases)
Dizziness
Fall
Femur fracture

60+:

Drug ineffective
Myalgia (muscle pain)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)
Blood pressure increased

What are the existing conditions these people have? *

Hypersensitivity: 16 people, 22.54%
High Blood Pressure: 14 people, 19.72%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 16.90%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 15.49%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 14.08%
Osteoporosis (bones weak and more likely to break): 8 people, 11.27%
Back Pain: 8 people, 11.27%
Sinus Disorder (disease of sinus): 7 people, 9.86%
Asthma: 7 people, 9.86%
Stress And Anxiety: 7 people, 9.86%

* Approximation only. Some reports may have incomplete information.

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