Aldactone and Bicalutamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Aldactone (spironolactone) and Bicalutamide (bicalutamide). Common drug interactions include drug specific antibody present among females and injection site erythema among males.
The phase IV clinical study analyzes what interactions people have when they take Aldactone and Bicalutamide. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Aldactone?
Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.
What is Bicalutamide?
Bicalutamide has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 9,930 Bicalutamide users. Check the latest studies of Bicalutamide.
20 people who take Aldactone and Bicalutamide together, and have interactions are studied.

What are the common drug interactions of Aldactone and Bicalutamide, by gender? *:
female:
- Drug specific antibody present
- Injection site haemorrhage (bleeding from injection site)
male:
- Injection site erythema (redness at injection site)
- Injection site induration
- Interstitial lung disease
- Oedema peripheral (superficial swelling)
- Arthralgia (joint pain)
- Back pain
- Cardiac failure congestive
- Chest pain
- Constipation
- Cytomegalovirus infection
What are the common drug interactions of Aldactone and Bicalutamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Injection site erythema (redness at injection site)
- Injection site induration
- Interstitial lung disease
- Oedema peripheral (superficial swelling)
- Arthralgia (joint pain)
- Back pain
- Cardiac failure congestive
- Chest pain
- Constipation
- Cytomegalovirus infection
What are the existing conditions these people have? *
- Cardiac Failure: 8 people, 40.00%
- Prostate Cancer Stage Iv: 7 people, 35.00%
- High Blood Pressure: 5 people, 25.00%
- Diabetes: 5 people, 25.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 25.00%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 20.00%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 20.00%
- Stable Angina (a constant chest pain): 4 people, 20.00%
- Gastritis (inflammation of stomach): 4 people, 20.00%
- Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Aldactone and Bicalutamide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Aldactone (46,063 reports)
- Bicalutamide (9,930 reports)
Browse all drug interactions of Aldactone and Bicalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aldactone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bicalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aldactone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bicalutamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on spironolactone and bicalutamide (the active ingredients of Aldactone and Bicalutamide, respectively), and Aldactone and Bicalutamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Aldactone and Thin Bones for Men aged 60+ - 3 seconds ago
- Aldactone and Osteoporosis for Men aged 60+ - 4 seconds ago
- Drug interactions of Tracleer and Victoza - 14 seconds ago
- Drug interactions of Gilenya and Ambien Cr - 21 seconds ago
- Could Orudis cause Thrombocytopenia? - 37 seconds ago
- Drug interactions of Lemtrada and Ritalin - 45 seconds ago
- Joint Pain in Eliquis, how severe and when it was recovered? - 48 seconds ago
- Drug interactions of Betamethasone Valerate and Vicodin - 49 seconds ago
- Drug interactions of Garlic and Apple Cider Vinegar - a minute ago
- Drug interactions of Gleevec and Pulmicort - a minute ago