Aldactone and Tekturna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aldactone (spironolactone) and Tekturna (aliskiren hemifumarate). Common drug interactions include gastrointestinal disorder among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aldactone and Tekturna. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

On Jul, 11, 2026

42 people who take Aldactone and Tekturna together, and have interactions are studied.

Aldactone and Tekturna drug interactions.

What are the common drug interactions of Aldactone and Tekturna, by gender? *:

female:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Rash
Asthma
Chest discomfort
Drug hypersensitivity
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure (kidney dysfunction)
Throat tightness
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hypotension (abnormally low blood pressure)
International normalised ratio decreased
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Nephrogenic anaemia (anaemia due to kidney disease)
Neutropenia (an abnormally low number of neutrophils)
Pancreatitis (inflammation of pancreas)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Platelet count decreased

What are the common drug interactions of Aldactone and Tekturna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pancreatitis (inflammation of pancreas)
Troponin increased
Acute myocardial infarction (acute heart attack)
Cholecystitis acute (rapid infection of gallbladder)
Gallbladder pain
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Neutropenia (an abnormally low number of neutrophils)
Papillary thyroid cancer
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Pleural effusion (water on the lungs)

40-49:

Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Asthma
Chest discomfort
Chronic kidney disease
Drug hypersensitivity
Palpitations (feelings or sensations that your heart is pounding or racing)
Rash
Renal failure (kidney dysfunction)
Throat tightness
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)

60+:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Activities of daily living impaired
Blood osmolarity increased
Constipation
Dyspnoea (difficult or laboured respiration)
Hair colour changes
Hair disorder
Hyperglycaemia (high blood sugar)
Inappropriate antidiuretic hormone secretion
Influenza

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 11.90%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 9.52%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 7.14%
Pain: 3 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.14%
Depression: 3 people, 7.14%
Asthma: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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