Centrum and Canasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Canasa (mesalamine). Common drug interactions include supraventricular tachycardia among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Canasa. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Canasa?

Canasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 1,676 Canasa users. Check the latest studies of Canasa.

On Jul, 11, 2026

23 people who take Centrum and Canasa together, and have interactions are studied.

What are the common drug interactions of Centrum and Canasa, by gender? *:

female:

Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Thrombosis (formation of a blood clot inside a blood vessel)
Urinary tract infection enterococcal
Vitamin d decreased
Faecal incontinence (a lack of control over passing stool)
Abdominal hernia
Acute respiratory failure
Bowel movement irregularity
Cardiac arrest
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Dizziness
Acne (skin problems that cause pimples)
Rash morbilliform (a rash that looks like measles)
Swelling face
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Frequent bowel movements

What are the common drug interactions of Centrum and Canasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Dizziness
Haematochezia (passage of stools containing blood)
Hot flush (sudden feelings of heat)
Pallor
Pyrexia (fever)
Rash
Rash generalised (rash on most of body parts)

30-39:

n/a

40-49:

Abdominal distension
Aphasia (damage to the parts of the brain that control language)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Costochondritis (chest wall pain)
Cutaneous lupus erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms)
Dehydration (dryness resulting from the removal of water)
Eye movement disorder

50-59:

Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dysgeusia (disorder of the sense of taste)
Eye discharge
Ocular hyperaemia (an abnormally large amount of blood in eye)

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Faecal incontinence (a lack of control over passing stool)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoxia (low oxygen in tissues)
Abdominal discomfort
Abdominal hernia
Anorectal disorder
Bowel movement irregularity

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 52.17%
High Blood Pressure: 6 people, 26.09%
High Blood Cholesterol: 6 people, 26.09%
Stress And Anxiety: 5 people, 21.74%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 13.04%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 13.04%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 13.04%
Hypokalemia (low potassium): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Depression: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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