Alendronate sodium and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alendronate sodium (alendronate sodium) and Soliris (eculizumab). Common drug interactions include haemoglobin increased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Alendronate sodium and Soliris. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 09, 2026

49 people who take Alendronate sodium and Soliris together, and have interactions are studied.

Alendronate sodium and Soliris drug interactions.

What are the common drug interactions of Alendronate Sodium and Soliris, by gender? *:

female:

Haemoglobin increased
Impaired healing
Local swelling (swelling at the site of some application of substance or injury)
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Multi-organ failure (multisystem organ failure)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Oedema (fluid collection in tissue)
Papillary thyroid cancer
Pulmonary embolism (blockage of the main artery of the lung)
Skin cancer

male:

Pyrexia (fever)
Abdominal pain
Blood magnesium decreased
Cardiovascular disorder (heart diseases)
Death
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Erythema (redness of the skin)

What are the common drug interactions of Alendronate Sodium and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Leukocytosis (increased white blood cells)
Pulmonary tuberculosis (lungs tuberculosis)

20-29:

Anxiety
Erythema (redness of the skin)
Fear
Feeling hot
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Injection site urticaria (rash of round, red welts on the skin at injection site)
Local swelling (swelling at the site of some application of substance or injury)
Pruritus (severe itching of the skin)
Thrombosis (formation of a blood clot inside a blood vessel)

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Joint swelling
Pain in extremity
Papillary thyroid cancer
Pulmonary embolism (blockage of the main artery of the lung)
Thyroidectomy

40-49:

Abdominal pain
Acne (skin problems that cause pimples)
Faeces discoloured
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Pyrexia (fever)
Eyelid ptosis (falling of the upper or lower eyelid)
Arthralgia (joint pain)
Blood lactate dehydrogenase increased
Haemoglobin decreased
Myalgia (muscle pain)

50-59:

Thyroid cancer
Erythema (redness of the skin)
Oedema peripheral (superficial swelling)
Vomiting
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Feeling hot
Local swelling (swelling at the site of some application of substance or injury)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Oedema (fluid collection in tissue)

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Flushing (the warm, red condition of human skin)
Gait disturbance
Headache (pain in head)
Hypertension (high blood pressure)
Muscle spasms (muscle contraction)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Oedema peripheral (superficial swelling)
Oral disorder (mouth disease)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 32 people, 65.31%
Diabetes: 9 people, 18.37%
High Blood Pressure: 6 people, 12.24%
Sleep Disorder: 5 people, 10.20%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.16%
Haemoglobin Decreased: 4 people, 8.16%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 4 people, 8.16%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 8.16%
Nausea (feeling of having an urge to vomit): 3 people, 6.12%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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