Aleve pm and Magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve pm (diphenhydramine hydrochloride; naproxen sodium) and Magnesium (magnesium). Common drug interactions include haemoglobin decreased among females and arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve pm and Magnesium. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve pm?

Aleve pm has active ingredients of diphenhydramine hydrochloride; naproxen sodium. eHealthMe is studying from 2,094 Aleve pm users. Check the latest studies of Aleve pm.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,145 Magnesium users. Check the latest studies of Magnesium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

15 people who take Aleve pm and Magnesium together, and have interactions are studied.

Aleve pm and Magnesium drug interactions.

What are the common drug interactions of Aleve Pm and Magnesium, by gender? *:

female:

Haemoglobin decreased
Heart rate decreased
Monoclonal immunoglobulin present
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Abnormal behaviour
Diarrhoea
Drug ineffective
Gastrointestinal disorder (functional problems of gastrointestinal tract)

male:

Arrhythmia (irregular heartbeat)
Colitis (inflammation of colon)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)

What are the common drug interactions of Aleve Pm and Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abnormal behaviour

50-59:

Colitis (inflammation of colon)
Diarrhoea

60+:

Arrhythmia (irregular heartbeat)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

Sleep Disorder: 4 people, 26.67%
Tumor: 2 people, 13.33%
Headache (pain in head): 2 people, 13.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 13.33%
Blood Pressure Abnormal: 2 people, 13.33%
Colitis (inflammation of colon): 2 people, 13.33%
Diabetes: 2 people, 13.33%
Diarrhea: 2 people, 13.33%
Essential Tremor: 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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