Aleve and Flecainide acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve (naproxen sodium) and Flecainide acetate (flecainide acetate). Common drug interactions include constipation among females and akathisia among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve and Flecainide acetate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

14 people who take Aleve and Flecainide acetate together, and have interactions are studied.

Aleve and Flecainide acetate drug interactions.

What are the common drug interactions of Aleve and Flecainide Acetate, by gender? *:

female:

Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Dyspepsia (indigestion)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypokalaemia (low potassium)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)

male:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anxiety
Diarrhoea
Drug hypersensitivity
Dry mouth
Dyskinesia (abnormality or impairment of voluntary movement)
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional disorder
Flushing (the warm, red condition of human skin)
Gait disturbance

What are the common drug interactions of Aleve and Flecainide Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anxiety
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

60+:

Diarrhoea
Constipation
Nausea (feeling of having an urge to vomit)
Starvation (a severe deficiency in caloric energy, nutrient, and vitamin intake)
Vomiting
White blood cell count decreased
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Alopecia (absence of hair from areas of the body)
Anxiety
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)

What are the existing conditions these people have? *

Depression: 2 people, 14.29%
High Blood Cholesterol: 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Lacrimation Increased: 1 person, 7.14%
Gout (uric acid crystals building up in the body): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 7.14%
Ill-Defined Disorder: 1 person, 7.14%
Indigestion: 1 person, 7.14%
Irritable Bowel Syndrome: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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