Aleve and Vigamox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve (naproxen sodium) and Vigamox (moxifloxacin hydrochloride). Common drug interactions include abnormal sensation in eye among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve and Vigamox. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Vigamox?

Vigamox has active ingredients of moxifloxacin hydrochloride. It is often used in conjunctivitis. eHealthMe is studying from 2,899 Vigamox users. Check the latest studies of Vigamox.

On Jul, 12, 2026

11 people who take Aleve and Vigamox together, and have interactions are studied.

What are the common drug interactions of Aleve and Vigamox, by gender? *:

female:

Abnormal sensation in eye
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Arthralgia (joint pain)
Arthropathy
Cystoid macular oedema (fluid accumulation after cataract surgery)
Macular cyst (retinal hole)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Sinus congestion (blockage of sinus)

male:

Renal failure (kidney dysfunction)
Gastric cancer (stomach cancer)
Renal injury (kidney injury)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Dyspepsia (indigestion)
Full blood count decreased
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Aleve and Vigamox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Injection site irritation

40-49:

n/a

50-59:

n/a

60+:

Renal failure (kidney dysfunction)
Abnormal sensation in eye
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Renal injury (kidney injury)
Sinus congestion (blockage of sinus)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Vision blurred
Visual acuity reduced (reduced clearness of vision)
Visual acuity reduced transiently

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 45.45%
Vitamin B Complex Deficiency: 3 people, 27.27%
Infection: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 18.18%
Retinal Oedema (swelling of retina): 2 people, 18.18%
Mydriasis (a dilation of the pupil): 2 people, 18.18%
Diabetic Eye Disease: 2 people, 18.18%
Vitamin D Decreased: 2 people, 18.18%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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