Aleve and Viibryd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aleve (naproxen sodium) and Viibryd (vilazodone hydrochloride). Common drug interactions include diarrhoea among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Aleve and Viibryd. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

What is Viibryd?

Viibryd has active ingredients of vilazodone hydrochloride. It is often used in depression. eHealthMe is studying from 11,106 Viibryd users. Check the latest studies of Viibryd.

On Jul, 31, 2026

61 people who take Aleve and Viibryd together, and have interactions are studied.

What are the common drug interactions of Aleve and Viibryd, by gender? *:

female:

Diarrhoea
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Dizziness
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Contusion (a type of hematoma of tissue in which capillaries)
Vaginal haemorrhage (vaginal bleeding)
Alopecia (absence of hair from areas of the body)
Fall
Loss of consciousness

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Back disorder
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)
Petit mal epilepsy (absence seizure)
Sinusitis (inflammation of sinus)
Therapeutic response unexpected
Weight increased

What are the common drug interactions of Aleve and Viibryd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Ovarian cyst (fluid filled sac of the ovary)
Fatigue (feeling of tiredness)
Impaired work ability
Nephrolithiasis (calculi in the kidneys)
Ovarian cyst ruptured (tear in fluid filled sac of the ovary)
Sedation
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vomiting

30-39:

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Chronic kidney disease
Therapeutic response unexpected
Nightmare (unpleasant dream)
Obesity (having too much body fat)

40-49:

Drug ineffective
Swelling

50-59:

Vaginal haemorrhage (vaginal bleeding)
Somnolence (a state of near-sleep, a strong desire for sleep)
Dizziness
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Diarrhoea
Brain stem haemorrhage (bleeding into structures of brain stem)
Fatigue (feeling of tiredness)
Loss of consciousness

60+:

Acute myocardial infarction (acute heart attack)
Alopecia (absence of hair from areas of the body)
Joint stiffness
Loss of consciousness
Muscular weakness (muscle weakness)
Panic attack
Pneumonia
Procedural pain
Pyrexia (fever)
Abdominal pain upper

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 30 people, 49.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 24.59%
Hypersensitivity: 7 people, 11.48%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 11.48%
Migraine (headache): 6 people, 9.84%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 8.20%
Stress And Anxiety: 4 people, 6.56%
Cardiac Disorder: 4 people, 6.56%
Asthma: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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