Entecavir and Solu-cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entecavir (entecavir) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include arthralgia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Entecavir and Solu-cortef. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Entecavir?

Entecavir has active ingredients of entecavir. It is often used in hepatitis b. eHealthMe is studying from 7,354 Entecavir users. Check the latest studies of Entecavir.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.



On Jul, 31, 2026

14 people who take Entecavir and Solu-cortef together, and have interactions are studied.

Entecavir and Solu-cortef drug interactions.

What are the common drug interactions of Entecavir and Solu-Cortef, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  3. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Heart rate decreased
  6. Poor venous access
  7. Skin infection
  8. Blood pressure diastolic increased
  9. Blood pressure increased
  10. Erythema multiforme (a type of hypersensitivity reaction)

male:

  1. Pyrexia (fever)

What are the common drug interactions of Entecavir and Solu-Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood pressure diastolic increased
  2. Blood pressure increased
  3. Weight increased
  4. Arthralgia (joint pain)
  5. Heart rate decreased
  6. Poor venous access
  7. Skin infection

50-59:

  1. Erythema multiforme (a type of hypersensitivity reaction)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  2. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  3. Pyrexia (fever)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 71.43%
  2. Hepatitis B Core Antibody Positive: 10 people, 71.43%
  3. Febrile Neutropenia (fever with reduced white blood cells): 3 people, 21.43%
  4. Hyperglycemia (high blood sugar): 2 people, 14.29%
  5. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 2 people, 14.29%
  6. Back Pain: 2 people, 14.29%
  7. B-Cell Lymphoma Recurrent (blood cancer affecting b cells-recurrent): 2 people, 14.29%
  8. Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
  9. Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 1 person, 7.14%
  10. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Entecavir and Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Entecavir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Entecavir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-cortef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on entecavir and hydrocortisone sodium succinate (the active ingredients of Entecavir and Solu-cortef, respectively), and Entecavir and Solu-cortef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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