Allegra allergy and Xiidra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra allergy (fexofenadine hydrochloride) and Xiidra (lifitegrast). Common drug interactions include dizziness among females and tachycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra allergy and Xiidra. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra allergy?

Allegra allergy has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 13,594 Allegra allergy users. Check the latest studies of Allegra allergy.

What is Xiidra?

Xiidra has active ingredients of lifitegrast. eHealthMe is studying from 15,244 Xiidra users. Check the latest studies of Xiidra.

On Jul, 14, 2026

23 people who take Allegra allergy and Xiidra together, and have interactions are studied.

Allegra allergy and Xiidra drug interactions.

What are the common drug interactions of Allegra Allergy and Xiidra, by gender? *:

female:

Dizziness
Fall
Infusion related reaction
Nausea (feeling of having an urge to vomit)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Adverse drug reaction
Anaemia (lack of blood)
Back pain

male:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Arthralgia (joint pain)
Visual impairment
Dehydration (dryness resulting from the removal of water)
Spinal disorder (disease of spine a back bone)
Viral infection
Vomiting
Spinal pain (pain in spine)
Acne (skin problems that cause pimples)
Gait disturbance

What are the common drug interactions of Allegra Allergy and Xiidra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Depression
Hospitalisation
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Viral infection
Vomiting
Anaemia (lack of blood)
Connective tissue disorder (any disease that has the connective tissues of the body)
Dehydration (dryness resulting from the removal of water)

40-49:

Surgery
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)

50-59:

Face injury
Fall
Tooth injury

60+:

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 39.13%
Drowsiness: 6 people, 26.09%
Pain: 3 people, 13.04%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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