Omeprazole and Arzerra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Arzerra (ofatumumab). Common drug interactions include gastroenteritis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Arzerra. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Arzerra?

Arzerra has active ingredients of ofatumumab. eHealthMe is studying from 1,042 Arzerra users. Check the latest studies of Arzerra.



On Jul, 14, 2026

15 people who take Omeprazole and Arzerra together, and have interactions are studied.

Omeprazole and Arzerra drug interactions.

What are the common drug interactions of Omeprazole and Arzerra, by gender? *:

female:

  1. Gastroenteritis (inflammation of stomach and intestine)
  2. Hepatic enzyme increased
  3. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  4. Dyspnoea (difficult or laboured respiration)
  5. Erythema of eyelid (redness of the eyelid)
  6. Eyelid oedema (eyelids are swollen and contain excessive fluid)
  7. Lip oedema (swelling of lip)
  8. Nausea (feeling of having an urge to vomit)
  9. Oxygen saturation decreased
  10. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

male:

  1. Diarrhoea
  2. Bradycardia (abnormally slow heart action)
  3. General physical health deterioration (weak health status)
  4. Heart rate decreased
  5. Hypoxia (low oxygen in tissues)
  6. Immunodeficiency
  7. Interstitial lung disease
  8. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Omeprazole and Arzerra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Bradycardia (abnormally slow heart action)
  2. Electrocardiogram qt prolonged
  3. Heart rate decreased
  4. Arrhythmia (irregular heartbeat)
  5. Atrioventricular block second degree (heart block second degree)
  6. Blood calcium decreased
  7. Hypokalaemia (low potassium)
  8. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hepatic haemorrhage (bleeding inside liver)
  2. Abdominal pain upper
  3. Gastroenteritis (inflammation of stomach and intestine)
  4. Hepatic enzyme increased

50-59:

  1. Asthenia (weakness)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Cough
  4. Diarrhoea
  5. Disease progression
  6. Dizziness
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. General physical health deterioration (weak health status)
  9. Hypoxia (low oxygen in tissues)
  10. Immunodeficiency

60+:

  1. Diarrhoea
  2. Face injury
  3. Oxygen saturation decreased
  4. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  5. Pneumonia
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  7. Pyrexia (fever)
  8. Sensory disturbance (sense disturbance)
  9. Vertigo
  10. Vomiting

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 46.67%
  2. High Blood Pressure: 2 people, 13.33%
  3. High Blood Cholesterol: 2 people, 13.33%
  4. Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 6.67%
  5. Chronic Lymphocytic Leukaemia Recurrent (repeated cancer of blood cells known as lymphocytes): 1 person, 6.67%
  6. Diabetes: 1 person, 6.67%
  7. Diarrhea: 1 person, 6.67%
  8. Dyslipidaemia (abnormal amount of lipids): 1 person, 6.67%
  9. Hepatitis B: 1 person, 6.67%
  10. Viral Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Omeprazole and Arzerra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arzerra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arzerra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and ofatumumab (the active ingredients of Omeprazole and Arzerra, respectively), and Omeprazole and Arzerra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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