Allegra and Dimetapp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Dimetapp (brompheniramine maleate; phenylpropanolamine hydrochloride). Common drug interactions include pruritus among females and sinusitis among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Dimetapp. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

What is Dimetapp?

Dimetapp has active ingredients of brompheniramine maleate; phenylpropanolamine hydrochloride. It is often used in cough. eHealthMe is studying from 4,740 Dimetapp users. Check the latest studies of Dimetapp.

On Jul, 26, 2026

29 people who take Allegra and Dimetapp together, and have interactions are studied.

What are the common drug interactions of Allegra and Dimetapp, by gender? *:

female:

Pruritus (severe itching of the skin)
Anxiety
Blood pressure increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Dry eye (lack of adequate tears)
Dry skin
Emotional distress
Eye pruritus (eye itching)

male:

Sinusitis (inflammation of sinus)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Infusion related reaction
Breast cancer male
Breast lump (localized swelling that feels different from the surrounding breast tissue)
Skin irritation
Breast cancer
Breast cancer female
Electrocardiogram qrs complex prolonged
Electrocardiogram st segment elevation

What are the common drug interactions of Allegra and Dimetapp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Drug ineffective

10-19:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Loss of consciousness
Intraventricular haemorrhage (intraventricular bleeding)
Oedema (fluid collection in tissue)
Thalamus haemorrhage (bleeding in thalamus)

20-29:

Arrhythmia (irregular heartbeat)
Cardiac arrest
Hyperpyrexia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious)
Electrocardiogram qrs complex prolonged
Electrocardiogram st segment elevation
Hyperkalaemia (damage to or disease of the kidney)
Muscle disorder (muscle disease)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

30-39:

Anxiety
Blood pressure increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Emotional distress
Mood swings (an extreme or rapid change in mood)
Pain

40-49:

Drug hypersensitivity

50-59:

Abdominal discomfort
Blood cholesterol increased
Early satiety (feeling full before completing a normal sized meal)
Flatulence (flatus expelled through the anus)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hunger
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Throat irritation

60+:

Pruritus (severe itching of the skin)
Breast cancer male
Night blindness (inability to see in night as day)
Rash pruritic (redness with itching)
Skin erosion (a discontinuity of the skin)
Skin irritation
Vision blurred
Visual impairment
Breast cancer
Breast cancer female

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 27.59%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 5 people, 17.24%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 13.79%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 10.34%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 3 people, 10.34%
Multiple Allergies (allergy to multiple agents): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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