Allegra and Enablex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Enablex (darifenacin hydrobromide). Common drug interactions include tendonitis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Enablex. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

What is Enablex?

Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.

On Jul, 15, 2026

69 people who take Allegra and Enablex together, and have interactions are studied.

What are the common drug interactions of Allegra and Enablex, by gender? *:

female:

Tendonitis (a condition that causes pain and swelling of tendons)
Pneumonia
Bone disorder
Cough
Heart rate increased
Neck pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Pathological fracture (broken bone caused by disease)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dysstasia (difficulty in standing)
Femur fracture
Fracture delayed union (delayed cure of broken bone)
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Haematoma (collection of blood outside the blood vessels)
Hypersensitivity

What are the common drug interactions of Allegra and Enablex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Adjustment disorder
Fall
Foot fracture
Initial insomnia (feeling of inadequate or poor-quality sleep)
Wrist surgery

20-29:

Ankylosing spondylitis (type of arthritis affecting the spine)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Femur fracture
Depression
Fall
Forearm fracture (fracture in between wrist to elbow)
Gastric ulcer (stomach ulcer)
Gastritis (inflammation of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lower limb fracture
Oesophageal spasm (contraction of oesophagus)

40-49:

Arthralgia (joint pain)
Back pain
Emotional disorder
Oedema peripheral (superficial swelling)
Pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Dependence
Drug abuse
Drug ineffective

50-59:

Bone density decreased
Bone disorder
Calcium deficiency (lack of calcium)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Disturbance in attention
Dizziness
Fall
Multiple fractures
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

60+:

Chronic kidney disease
Dysphonia (speech disorder attributable to a disorder of phonation)
Renal injury (kidney injury)
Blood pressure increased
Acute sinusitis
Altered state of consciousness (altered state of mind)
Anxiety
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bladder cancer recurrent

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 21.74%
High Blood Pressure: 12 people, 17.39%
Allergic Rhinitis: 10 people, 14.49%
Depression: 9 people, 13.04%
Pain: 9 people, 13.04%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 13.04%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 13.04%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 8 people, 11.59%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 10.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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