Allegra and Methyldopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Methyldopa (methyldopa). Common drug interactions include insomnia among females and acne among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Methyldopa. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,498 Allegra users. Check the latest studies of Allegra.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.



On Aug, 01, 2026

27 people who take Allegra and Methyldopa together, and have interactions are studied.

Allegra and Methyldopa drug interactions.

What are the common drug interactions of Allegra and Methyldopa, by gender? *:

female:

  1. Insomnia (sleeplessness)
  2. Pain in extremity
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Chest pain
  6. Cluster headache (one-sided head pain with tearing)
  7. Diarrhoea
  8. Drug ineffective
  9. Nausea (feeling of having an urge to vomit)
  10. Weight decreased

male:

  1. Acne (skin problems that cause pimples)
  2. Arthralgia (joint pain)
  3. Anxiety
  4. Asthma
  5. Cough
  6. Disturbance in attention
  7. Dysphemia (stammering or stuttering)
  8. Dyspnoea (difficult or laboured respiration)
  9. Emotional disorder
  10. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

What are the common drug interactions of Allegra and Methyldopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cachexia (loss of weight)
  2. Cancer pain
  3. Delivery
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Metastases to liver (cancer spreads to liver)
  6. Metastases to lymph nodes (cancer spreads to lymph node)
  7. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  8. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

50-59:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Chest pain
  4. Cluster headache (one-sided head pain with tearing)
  5. Diarrhoea
  6. Drug ineffective
  7. Insomnia (sleeplessness)
  8. Nausea (feeling of having an urge to vomit)
  9. Pain in extremity
  10. Weight decreased

60+:

  1. Fall
  2. Femur fracture
  3. Adverse event
  4. Arthralgia (joint pain)
  5. Bone disorder
  6. Fracture displacement
  7. Oral pruritus (itching in mouth)
  8. Pain in extremity
  9. Pruritus (severe itching of the skin)
  10. Throat tightness

What are the existing conditions these people have? *

  1. Stress And Anxiety: 8 people, 29.63%
  2. High Blood Cholesterol: 7 people, 25.93%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 25.93%
  4. Indigestion: 6 people, 22.22%
  5. Nausea (feeling of having an urge to vomit): 6 people, 22.22%
  6. Cough: 6 people, 22.22%
  7. Migraine (headache): 5 people, 18.52%
  8. Nervousness: 5 people, 18.52%
  9. Irritable Bowel Syndrome: 5 people, 18.52%
  10. Depression: 5 people, 18.52%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and Methyldopa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allegra and Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methyldopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride and methyldopa (the active ingredients of Allegra and Methyldopa, respectively), and Allegra and Methyldopa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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