Allegra and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Questran (cholestyramine). Common drug interactions include rash among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Questran. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,498 Allegra users. Check the latest studies of Allegra.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

99 people who take Allegra and Questran together, and have interactions are studied.

Allegra and Questran drug interactions.

What are the common drug interactions of Allegra and Questran, by gender? *:

female:

  1. Rash
  2. Cardiac arrest
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  5. Pyrexia (fever)
  6. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  7. Drug dependence
  8. Hepatic steatosis (fatty liver disease)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Abdominal pain upper

male:

  1. Abdominal pain
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  4. Dehydration (dryness resulting from the removal of water)
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Infection
  8. Renal failure (kidney dysfunction)
  9. Anaemia (lack of blood)
  10. Anaemia of malignant disease

What are the common drug interactions of Allegra and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cholecystitis acute (rapid infection of gallbladder)
  2. Abdominal pain
  3. Tracheitis (an inflammation of the trachea)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Dehydration (dryness resulting from the removal of water)

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Anxiety
  3. Biliary colic
  4. Blood pressure increased
  5. Body temperature decreased
  6. Cholecystitis chronic (long lasting infection of gallbladder)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  9. Cystic fibrosis (disease of the secretary glands)
  10. Decreased appetite

40-49:

  1. Abdominal pain
  2. Abdominal pain upper
  3. Diarrhoea haemorrhagic (bloody diarrhoea)
  4. Drug ineffective
  5. Dry skin
  6. Dyspnoea (difficult or laboured respiration)
  7. Female genital tract fistula (passage in genital tract of female)
  8. Fungal infection
  9. Oesophageal candidiasis (fungal infection of oesophagus)
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

  1. Cardiac arrest
  2. Dehydration (dryness resulting from the removal of water)
  3. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  4. Pneumonia
  5. Pyrexia (fever)
  6. Rash
  7. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  8. Drug dependence
  9. Hepatic steatosis (fatty liver disease)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

  1. Abdominal pain
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Hypertension (high blood pressure)
  4. Renal failure (kidney dysfunction)
  5. Depression
  6. Dyspnoea (difficult or laboured respiration)
  7. Emotional distress
  8. Haemoglobin decreased
  9. Infection
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 15.15%
  2. High Blood Pressure: 11 people, 11.11%
  3. Nausea (feeling of having an urge to vomit): 10 people, 10.10%
  4. Pain: 9 people, 9.09%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 8.08%
  6. Depression: 8 people, 8.08%
  7. Multiple Allergies (allergy to multiple agents): 7 people, 7.07%
  8. Insomnia (sleeplessness): 7 people, 7.07%
  9. Stress And Anxiety: 6 people, 6.06%
  10. Osteoporosis (bones weak and more likely to break): 6 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and Questran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allegra and Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Questran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride and cholestyramine (the active ingredients of Allegra and Questran, respectively), and Allegra and Questran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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