Allegra and Sprycel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Sprycel (dasatinib). Common drug interactions include renal failure acute among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Sprycel. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.



On Jul, 26, 2026

70 people who take Allegra and Sprycel together, and have interactions are studied.

Allegra and Sprycel drug interactions.

What are the common drug interactions of Allegra and Sprycel, by gender? *:

female:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Respiratory syncytial virus infection (viral disease of respiratory system)
  3. Stomatitis (inflammation of mucous membrane of mouth)
  4. Varicose vein (veins that have become enlarged and tortuous)
  5. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  6. Diarrhoea
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Drug hypersensitivity
  9. Nausea (feeling of having an urge to vomit)
  10. Cardiac failure

male:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Nausea (feeling of having an urge to vomit)
  3. Swollen tongue (swelling of tongue)
  4. Vomiting
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Neuropathy peripheral (surface nerve damage)
  7. Sneezing
  8. Swelling face
  9. Abdominal pain
  10. Adverse event

What are the common drug interactions of Allegra and Sprycel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood bilirubin increased
  2. Diarrhoea
  3. Drug intolerance (drug sensitivity)
  4. Dysstasia (difficulty in standing)
  5. Headache (pain in head)
  6. Nausea (feeling of having an urge to vomit)
  7. Papule
  8. Pruritus (severe itching of the skin)
  9. Pyrexia (fever)

20-29:

n/a

30-39:

  1. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Diarrhoea
  4. Drug hypersensitivity
  5. Nausea (feeling of having an urge to vomit)
  6. Cardiac failure
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Vomiting
  9. Eating disorder
  10. Fatigue (feeling of tiredness)

40-49:

  1. Abdominal pain
  2. Blood glucose increased
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Injection site erythema (redness at injection site)
  5. Injection site pain
  6. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  7. Pleural effusion (water on the lungs)
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Disease progression
  4. Dyspnoea (difficult or laboured respiration)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Heart rate increased
  7. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
  8. Rash

60+:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Peripheral swelling
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Haematemesis (vomiting of blood)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Influenza like illness
  8. Nausea (feeling of having an urge to vomit)
  9. Platelet count decreased
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 31 people, 44.29%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 11 people, 15.71%
  3. Wheezing (a high-pitched whistling sound made while you breath): 6 people, 8.57%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 8.57%
  5. Neoplasm Malignant (cancer tumour): 6 people, 8.57%
  6. Dyspnea (difficult or laboured breathing): 6 people, 8.57%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 8.57%
  8. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 7.14%
  9. Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 5.71%
  10. Cardiac Disorder: 4 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allegra and Sprycel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sprycel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sprycel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride and dasatinib (the active ingredients of Allegra and Sprycel, respectively), and Allegra and Sprycel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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