Allegra and Topicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Topicort (desoximetasone). Common drug interactions include pain among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Topicort. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

What is Topicort?

Topicort has active ingredients of desoximetasone. eHealthMe is studying from 3,423 Topicort users. Check the latest studies of Topicort.



On Jul, 28, 2026

30 people who take Allegra and Topicort together, and have interactions are studied.

Allegra and Topicort drug interactions.

What are the common drug interactions of Allegra and Topicort, by gender? *:

female:

  1. Pain
  2. Skin exfoliation (removal of the oldest dead skin cells)
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Axillary mass
  5. Axillary pain
  6. Drug ineffective
  7. Injection site bruising
  8. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  9. Neoplasm (tumour)
  10. Ovarian mass (mass in ovary)

male:

  1. Asthenia (weakness)
  2. Blood creatinine increased
  3. Peroneal nerve palsy
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  6. Aortic dilatation
  7. Arthralgia (joint pain)
  8. Cardiac failure
  9. Cardiomyopathy (weakening of the heart muscle)
  10. Cardiovascular insufficiency (inadequate functioning of heart)

What are the common drug interactions of Allegra and Topicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Asthenia (weakness)
  3. Swelling
  4. Swelling face
  5. Urticaria (rash of round, red welts on the skin that itch intensely)

20-29:

n/a

30-39:

  1. Anxiety
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Faecaloma (hard mass of fecal matter)
  4. Haematoma (collection of blood outside the blood vessels)
  5. Injection site bruising
  6. Injection site pain
  7. Injury
  8. Local swelling (swelling at the site of some application of substance or injury)
  9. Muscle atrophy (a decrease in the mass of the muscle)
  10. Overdose

40-49:

  1. Axillary mass
  2. Axillary pain
  3. Headache (pain in head)
  4. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  5. Neoplasm (tumour)
  6. Ovarian mass (mass in ovary)
  7. Anaplastic large cell lymphoma t- and null-cell types (t-cell or null-cell cancer, a type of blood cancer)
  8. Dental necrosis (tissue inside a tooth dies)
  9. Sensitivity of teeth
  10. Abscess (pus)

50-59:

  1. Injection site haemorrhage (bleeding from injection site)
  2. Injection site bruising
  3. Injection site pain
  4. Abdominal pain upper
  5. Breath sounds
  6. Cardiac failure congestive
  7. Dizziness
  8. Feeling cold
  9. Headache (pain in head)
  10. Hyperhidrosis (abnormally increased sweating)

60+:

  1. Pruritus (severe itching of the skin)
  2. Anaemia (lack of blood)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Upper respiratory tract infection
  5. Drug ineffective
  6. Fatigue (feeling of tiredness)
  7. Alopecia (absence of hair from areas of the body)
  8. Asthenia (weakness)
  9. Blood creatinine increased
  10. Cardiac failure

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 12 people, 40.00%
  2. Psoriasis (immune-mediated disease that affects the skin): 8 people, 26.67%
  3. Multiple Allergies (allergy to multiple agents): 6 people, 20.00%
  4. Asthma: 6 people, 20.00%
  5. Itching: 5 people, 16.67%
  6. High Blood Cholesterol: 4 people, 13.33%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 13.33%
  8. Urinary Tract Infection: 3 people, 10.00%
  9. Pain: 3 people, 10.00%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Allegra and Topicort?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allegra and Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allegra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride and desoximetasone (the active ingredients of Allegra and Topicort, respectively), and Allegra and Topicort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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