Allegra and Tranexamic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra (fexofenadine hydrochloride) and Tranexamic acid (tranexamic acid). Common drug interactions include blood urea increased among females and rib fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra and Tranexamic acid. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,498 Allegra users. Check the latest studies of Allegra.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

45 people who take Allegra and Tranexamic acid together, and have interactions are studied.

Allegra and Tranexamic acid drug interactions.

What are the common drug interactions of Allegra and Tranexamic Acid, by gender? *:

female:

Blood urea increased
Cellulitis (infection under the skin)
Cerebral haemorrhage (bleeding within the brain)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chest pain
Coagulopathy (blood's ability to clot is impaired)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Disturbance in attention
Dizziness

male:

Rib fracture
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Pyrexia (fever)
Anxiety
Depression
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Laryngeal disorder (disease of larynx related to voice)
Libido increased (increased sexual urge to have sex)
Post procedural complication
Therapeutic response decreased (less preventive response)

What are the common drug interactions of Allegra and Tranexamic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood creatine phosphokinase increased
Gastroenteritis (inflammation of stomach and intestine)
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Osteonecrosis (death of bone)
Otitis externa (external ear infection)
Purpura (purplish discoloration of the skin)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)

30-39:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Rib fracture
Sleep-related eating disorder (abnormal eating patterns during the night)
Weight decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Laryngeal disorder (disease of larynx related to voice)
Post procedural complication
Vocal cord paralysis
Disability

40-49:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Abdominal pain
Alanine aminotransferase increased
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Application site pruritus (application site severe itching of the skin)
Aspartate aminotransferase increased
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

50-59:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)

60+:

Pyrexia (fever)
Muscle abscess (pus in muscle)
Pneumonia
Renal impairment (severely reduced kidney function)
Haemolytic anaemia (anaemia due to haemolysis)
Oedema peripheral (superficial swelling)
Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Albumin urine present
Ammonia increased
Arthralgia (joint pain)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 28.89%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 22.22%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 6 people, 13.33%
Productive Cough: 6 people, 13.33%
Back Pain: 6 people, 13.33%
Constipation: 6 people, 13.33%
Cough: 6 people, 13.33%
Coughing Up Blood: 6 people, 13.33%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 6 people, 13.33%
Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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