Allopurinol and Drisdol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allopurinol (allopurinol) and Drisdol (ergocalciferol). Common drug interactions include pulmonary congestion among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Allopurinol and Drisdol. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.



On Jul, 21, 2026

71 people who take Allopurinol and Drisdol together, and have interactions are studied.

Allopurinol and Drisdol drug interactions.

What are the common drug interactions of Allopurinol and Drisdol, by gender? *:

female:

  1. Pulmonary congestion (congestion in the lungs)
  2. Urinary tract infection
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Ageusia (loss of taste functions of the tongue)
  5. Anaemia (lack of blood)
  6. Angioedema (rapid swelling of the dermis)
  7. Arthralgia (joint pain)
  8. Blood calcium decreased
  9. Blood glucose increased
  10. Blood iron decreased

male:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Sudden cardiac death
  4. Fatigue (feeling of tiredness)
  5. Back pain
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Pain
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Renal tubular necrosis (death of kidney tubules)
  10. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Allopurinol and Drisdol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Angioedema (rapid swelling of the dermis)
  2. Dyspnoea (difficult or laboured respiration)
  3. Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

n/a

40-49:

n/a

50-59:

  1. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Clavicle fracture
  4. Decreased activity
  5. Depression
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Emotional distress
  8. Fatigue (feeling of tiredness)
  9. Fracture
  10. Fractured coccyx (fracture tail bone)

60+:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Abdominal distension
  4. Acute sinusitis
  5. Atelectasis (partial or complete collapse of the lung)
  6. Brain natriuretic peptide increased
  7. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  8. Colitis (inflammation of colon)
  9. Deafness
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 22.54%
  2. Multiple Myeloma (cancer of the plasma cells): 12 people, 16.90%
  3. Hyperkalemia (damage to or disease of the kidney): 11 people, 15.49%
  4. Pain: 9 people, 12.68%
  5. Anaemia (lack of blood): 8 people, 11.27%
  6. High Blood Pressure: 7 people, 9.86%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 8.45%
  8. Infection: 6 people, 8.45%
  9. High Blood Cholesterol: 6 people, 8.45%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Allopurinol and Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allopurinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on allopurinol and ergocalciferol (the active ingredients of Allopurinol and Drisdol, respectively), and Allopurinol and Drisdol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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