Aloe vera and Centrum drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Aloe vera (aloe) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include cough among females and injection site haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Aloe vera and Centrum. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Aloe vera?
Aloe vera has active ingredients of aloe. eHealthMe is studying from 1,457 Aloe vera users. Check the latest studies of Aloe vera.
What is Centrum?
Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.
26 people who take Aloe vera and Centrum together, and have interactions are studied.

What are the common drug interactions of Aloe Vera and Centrum, by gender? *:
female:
- Cough
- Nausea (feeling of having an urge to vomit)
- Contusion (a type of hematoma of tissue in which capillaries)
- Diarrhoea
- Dizziness
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Insomnia (sleeplessness)
- Joint swelling
male:
- Injection site haemorrhage (bleeding from injection site)
- Injection site pain
- Abdominal pain upper
- Oedema peripheral (superficial swelling)
- Rash macular (small, flat red spots)
- Drug ineffective
- Injection site discomfort
- Vomiting
What are the common drug interactions of Aloe Vera and Centrum, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Drug ineffective
- Vomiting
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Dysarthria (speech disorder)
- Gait disturbance
- Hallucination (an experience involving the perception of something not present)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Nasopharyngitis (inflammation of the nasopharynx)
- Rash
- Rash pruritic (redness with itching)
- Retinal pigmentation (pigmentation of retina)
60+:
- Cough
- Asthenia (weakness)
- Blood chloride decreased
- Blood sodium decreased
- Contusion (a type of hematoma of tissue in which capillaries)
- Dizziness
- Emotional distress
- Haemoglobin decreased
- Hypertension (high blood pressure)
- Infusion site bruising
What are the existing conditions these people have? *
- Stress And Anxiety: 6 people, 23.08%
- Ovarian Cancer (cancer of ovary): 5 people, 19.23%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 15.38%
- Immunodeficiency: 4 people, 15.38%
- Constipation: 4 people, 15.38%
- Migraine (headache): 3 people, 11.54%
- Insomnia (sleeplessness): 3 people, 11.54%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.54%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
- High Blood Pressure: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Aloe vera and Centrum?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Aloe vera and Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aloe vera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aloe vera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on aloe and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Aloe vera and Centrum, respectively), and Aloe vera and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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