Alphagan and Centrum silver drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include injection site pain among females and hypoglycaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Alphagan and Centrum silver. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.
What is Alphagan?
Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.
What is Centrum silver?
Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.
84 people who take Alphagan and Centrum silver together, and have interactions are studied.

What are the common drug interactions of Alphagan and Centrum Silver, by gender? *:
female:
- Injection site pain
- Insomnia (sleeplessness)
- Lung disorder (lung disease)
- Nail disorder (disease of nail)
- Nervousness
- Oedema peripheral (superficial swelling)
- Pain in extremity
- Peripheral coldness
- Poor quality sleep
- Pyrexia (fever)
male:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Influenza
- Conjunctival haemorrhage (bleeding underneath the conjunctiva)
- Cough
- Death
- Decreased appetite
- Depression
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Gastritis (inflammation of stomach)
What are the common drug interactions of Alphagan and Centrum Silver, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Tinnitus (a ringing in the ears)
- Weight decreased
- Blood glucose increased
- Injection site pain
- Back pain
- Diabetes mellitus inadequate control
- Dysphagia (a condition in which swallowing is difficult or painful)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Pain in extremity
60+:
- Pneumonia viral
- Cardiac failure congestive
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Asthenia (weakness)
- Cough
- Diastolic dysfunction
- Hyperglycaemia (high blood sugar)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
- Pain
What are the existing conditions these people have? *
- High Blood Pressure: 18 people, 21.43%
- Multiple Myeloma (cancer of the plasma cells): 12 people, 14.29%
- High Blood Cholesterol: 11 people, 13.10%
- Diabetes: 10 people, 11.90%
- Constipation: 9 people, 10.71%
- Back Pain: 8 people, 9.52%
- Osteoporosis (bones weak and more likely to break): 7 people, 8.33%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 8.33%
- Neuralgia (pain in one or more nerves): 6 people, 7.14%
- Abdominal Pain Upper: 6 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Alphagan and Centrum silver?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alphagan (9,981 reports)
- Centrum silver (19,997 reports)
Browse all drug interactions of Alphagan and Centrum silver:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Centrum silver:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum silver and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on brimonidine tartrate and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Alphagan and Centrum silver, respectively), and Alphagan and Centrum silver (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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