Alphagan and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Compazine (prochlorperazine maleate). Common drug interactions include dysplasia among females and cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan and Compazine. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 05, 2026

44 people who take Alphagan and Compazine together, and have interactions are studied.

Alphagan and Compazine drug interactions.

What are the common drug interactions of Alphagan and Compazine, by gender? *:

female:

Dysplasia (enlargement of an organ or tissue)
Emotional distress
Exostosis (formation of new bone on the surface of a bone)
Eye pain
Faecaloma (hard mass of fecal matter)
Fluid retention (an abnormal accumulation of fluid in the blood)
Foot deformity (functional disability of foot)
Fungal infection
Gait disturbance
Gallbladder disorder

male:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Essential tremor
Haemoglobin decreased
Haemorrhage (bleeding)
Insomnia (sleeplessness)
Lacunar infarction (a type of stroke)

What are the common drug interactions of Alphagan and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic calcification (aortic calcification sign of heart valve disease)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthropathy

60+:

Cough
Death
Dyspnoea (difficult or laboured respiration)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall
Hypertension (high blood pressure)
Lacunar infarction (a type of stroke)
Malaise (a feeling of general discomfort or uneasiness)
Muscle disorder (muscle disease)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 27.27%
Nausea (feeling of having an urge to vomit): 11 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.64%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 11.36%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 11.36%
Constipation: 5 people, 11.36%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 9.09%
Diarrhea: 4 people, 9.09%
Discomfort: 3 people, 6.82%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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