Alphagan and Vesicare drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Vesicare (solifenacin succinate). Common drug interactions include arrhythmia among females and intestinal obstruction among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan and Vesicare. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

On Aug, 09, 2026

34 people who take Alphagan and Vesicare together, and have interactions are studied.

Alphagan and Vesicare drug interactions.

What are the common drug interactions of Alphagan and Vesicare, by gender? *:

female:

Arrhythmia (irregular heartbeat)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Balance disorder
Blood cholesterol increased

male:

Intestinal obstruction
Dysphagia (a condition in which swallowing is difficult or painful)
Disability
Fear
Injury
Multi-organ failure (multisystem organ failure)
Pain
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Affective disorder (mental disorder)

What are the common drug interactions of Alphagan and Vesicare, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abscess (pus)
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arrhythmia (irregular heartbeat)
Arteriosclerosis (thickening and hardening of arteries)
Arthropathy
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain

40-49:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Constipation
Salivary hypersecretion (excess saliva secretion)

50-59:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased

60+:

Intestinal obstruction
Vomiting
Anxiety
Depression
Disability
Fear
Injury
Multi-organ failure (multisystem organ failure)
Pain
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 14.71%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.76%
High Blood Cholesterol: 4 people, 11.76%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 11.76%
Incontinence (lack of moderation or self-control): 3 people, 8.82%
Cardiac Disorder: 3 people, 8.82%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 8.82%
Aortic Valve Disease: 3 people, 8.82%
Neuropathy Peripheral (surface nerve damage): 3 people, 8.82%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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