Alprazolam and Actrapid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alprazolam (alprazolam) and Actrapid (insulin). Common drug interactions include dermatitis acneiform among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Alprazolam and Actrapid. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

What is Actrapid?

Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.



On Jul, 12, 2026

81 people who take Alprazolam and Actrapid together, and have interactions are studied.

Alprazolam and Actrapid drug interactions.

What are the common drug interactions of Alprazolam and Actrapid, by gender? *:

female:

  1. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  2. Hypertransaminasaemia
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Inflammation
  5. Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
  6. Joint effusion (presence of extra fluid in joint covering)
  7. Lactic acidosis (low ph in body tissues)
  8. Necrosis (the death of body tissue)
  9. Pleural effusion (water on the lungs)
  10. Pulmonary infarction (death of a small area of lung)

male:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Pleural effusion (water on the lungs)
  5. Aortic calcification (aortic calcification sign of heart valve disease)
  6. Ascites (accumulation of fluid in the abdominal cavity)
  7. Aspartate aminotransferase increased
  8. Atelectasis (partial or complete collapse of the lung)
  9. Bacterial test positive
  10. Blood alkaline phosphatase increased

What are the common drug interactions of Alprazolam and Actrapid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hyperglycaemia (high blood sugar)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Dysuria (painful or difficult urination)
  4. Electrocardiogram st-t change
  5. Oropharyngeal pain
  6. Pain
  7. Retching (strong involuntary effort to vomit)
  8. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Inflammation

40-49:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Poisoning deliberate
  5. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  6. Lactic acidosis (low ph in body tissues)
  7. Overdose

50-59:

  1. Back pain
  2. Erysipelas (bacterial skin infection)
  3. Viral infection
  4. Pneumonia
  5. General physical health deterioration (weak health status)
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Spinal compression fracture (fracture due to spinal compression on bone)

60+:

  1. Cardiac failure
  2. Colitis (inflammation of colon)
  3. Abdominal infection
  4. Cellulitis (infection under the skin)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  9. Peripheral ischaemia (impaired circulation to an extremity)
  10. Pleural effusion (water on the lungs)

What are the existing conditions these people have? *

  1. Diabetes: 39 people, 48.15%
  2. High Blood Cholesterol: 38 people, 46.91%
  3. Constipation: 28 people, 34.57%
  4. Pain: 25 people, 30.86%
  5. Hyperthyroidism (over activity of the thyroid gland): 24 people, 29.63%
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 24 people, 29.63%
  7. Poisoning Deliberate: 19 people, 23.46%
  8. High Blood Pressure: 18 people, 22.22%
  9. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 15 people, 18.52%
  10. Cough: 14 people, 17.28%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alprazolam and Actrapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alprazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actrapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alprazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actrapid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alprazolam and insulin (the active ingredients of Alprazolam and Actrapid, respectively), and Alprazolam and Actrapid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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