Alprazolam and Tribenzor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Alprazolam (alprazolam) and Tribenzor (amlodipine besylate; hydrochlorothiazide; olmesartan medoxomil). Common drug interactions include anaemia postoperative among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Alprazolam and Tribenzor. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Alprazolam?
Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.
What is Tribenzor?
Tribenzor has active ingredients of amlodipine besylate; hydrochlorothiazide; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 1,841 Tribenzor users. Check the latest studies of Tribenzor.
36 people who take Alprazolam and Tribenzor together, and have interactions are studied.

What are the common drug interactions of Alprazolam and Tribenzor, by gender? *:
female:
- Anaemia postoperative
- Type 2 diabetes mellitus
- Constipation
- Arthralgia (joint pain)
- Chronic kidney disease
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Malaise (a feeling of general discomfort or uneasiness)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Pain
- Peripheral swelling
- Renal tubular necrosis (death of kidney tubules)
- Skin disorder (skin disease)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Bedridden
- Bipolar disorder (mood disorder)
What are the common drug interactions of Alprazolam and Tribenzor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Constipation
- Hepatomegaly (abnormal enlargement of the liver)
- Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anaemia postoperative
- Asthenia (weakness)
- Blindness
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Fatigue (feeling of tiredness)
- Rectal haemorrhage (bleeding from anus)
- Type 2 diabetes mellitus
- Anastomotic ulcer haemorrhage
50-59:
- Chronic kidney disease
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal discomfort
- Adverse event
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Diarrhoea
- Dyspepsia (indigestion)
- Flushing (the warm, red condition of human skin)
60+:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pain
- Nephrolithiasis (calculi in the kidneys)
- Peripheral swelling
- Skin disorder (skin disease)
- Vomiting
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Chronic kidney disease
- Bedridden
- Feelings of worthlessness
What are the existing conditions these people have? *
- Pain: 10 people, 27.78%
- High Blood Cholesterol: 8 people, 22.22%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 19.44%
- Depression: 5 people, 13.89%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 11.11%
- Constipation: 4 people, 11.11%
- Insomnia (sleeplessness): 4 people, 11.11%
- Diarrhea: 4 people, 11.11%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.33%
- Diabetes: 3 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Alprazolam and Tribenzor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Alprazolam (134,864 reports)
- Tribenzor (1,841 reports)
Browse all drug interactions of Alprazolam and Tribenzor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Alprazolam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tribenzor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alprazolam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tribenzor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on alprazolam and amlodipine besylate; hydrochlorothiazide; olmesartan medoxomil (the active ingredients of Alprazolam and Tribenzor, respectively), and Alprazolam and Tribenzor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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