Senna and Peppermint oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Peppermint oil (peppermint). Common drug interactions include asthma among females and swelling face among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Peppermint oil. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Peppermint oil?

Peppermint oil has active ingredients of peppermint. eHealthMe is studying from 1,061 Peppermint oil users. Check the latest studies of Peppermint oil.



On Jul, 18, 2026

40 people who take Senna and Peppermint oil together, and have interactions are studied.

Senna and Peppermint oil drug interactions.

What are the common drug interactions of Senna and Peppermint Oil, by gender? *:

female:

  1. Asthma
  2. Cardiac arrest
  3. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  4. Lower respiratory tract infection
  5. Antipsychotic drug level increased
  6. Drug level increased
  7. Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
  8. Respiratory disorder (respiratory disease)
  9. Respiratory tract infection
  10. Lupus-like syndrome (a disease symptom matches with lupus an immune disease)

male:

  1. Swelling face
  2. Abdominal distension
  3. Blood pressure increased
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Decreased appetite
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Dehydration (dryness resulting from the removal of water)
  8. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  9. Diarrhoea
  10. Dizziness

What are the common drug interactions of Senna and Peppermint Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Device dislocation
  2. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  3. Weight gain poor

10-19:

  1. Abdominal distension
  2. Abdominal pain

20-29:

  1. Drug ineffective
  2. Neutropenia (an abnormally low number of neutrophils)

30-39:

  1. Diarrhoea
  2. Lip swelling
  3. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  4. Swelling face
  5. Vomiting

40-49:

  1. Asthma
  2. Cardiac arrest
  3. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  4. Antipsychotic drug level increased
  5. Drug level increased
  6. Lower respiratory tract infection
  7. Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
  8. Respiratory disorder (respiratory disease)
  9. Respiratory tract infection
  10. Eye swelling

50-59:

  1. Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
  2. Chest pain
  3. Confusional state
  4. Gingivitis (inflammation of gums)
  5. Lower respiratory tract infection
  6. Nausea (feeling of having an urge to vomit)
  7. Oral herpes (viral infection of mouth)
  8. Tooth abscess (pus formation in tooth)
  9. Upper respiratory tract infection
  10. Abdominal pain

60+:

  1. Angioedema (rapid swelling of the dermis)
  2. Bladder adenocarcinoma stage unspecified (bladder cancer stage unspecified)
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Swelling face
  6. Swollen tongue (swelling of tongue)
  7. Blood pressure increased
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  10. Dizziness

What are the existing conditions these people have? *

  1. Pain: 11 people, 27.50%
  2. Ill-Defined Disorder: 7 people, 17.50%
  3. Rashes (redness): 6 people, 15.00%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 15.00%
  5. Diabetes: 6 people, 15.00%
  6. Laxative Supportive Care: 5 people, 12.50%
  7. Oral Candidiasis (fungal infection of mouth): 5 people, 12.50%
  8. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 10.00%
  9. High Blood Pressure: 4 people, 10.00%
  10. Respiratory Disorder (respiratory disease): 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and Peppermint oil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Senna and Peppermint oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Peppermint oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peppermint oil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on senna and peppermint (the active ingredients of Senna and Peppermint oil, respectively), and Senna and Peppermint oil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: