Amaryl and Zoledronic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amaryl (glimepiride) and Zoledronic acid (zoledronic acid). Common drug interactions include anaemia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Amaryl and Zoledronic acid. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Zoledronic acid?

Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.

On Jul, 16, 2026

19 people who take Amaryl and Zoledronic acid together, and have interactions are studied.

Amaryl and Zoledronic acid drug interactions.

What are the common drug interactions of Amaryl and Zoledronic Acid, by gender? *:

female:

Anaemia (lack of blood)
Pain
Dry mouth
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Chronic kidney disease
Compression fracture (fracture due to pressure caused by injury)
Disease progression
Haemorrhage (bleeding)
Iron deficiency anaemia
Osteoporosis (bones weak and more likely to break)

male:

Pneumonia
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood sodium decreased
Bowel movement irregularity
C-reactive protein increased
Compression fracture (fracture due to pressure caused by injury)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased activity

What are the common drug interactions of Amaryl and Zoledronic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Fungal infection
Hyperchlorhydria (gastric acid levels are higher in stomach)
Limb discomfort (discomfort in leg)
Muscle spasms (muscle contraction)
Neoplasm progression (growth of tumour)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Pain
Anaemia (lack of blood)
Chronic kidney disease
Compression fracture (fracture due to pressure caused by injury)
Disease progression
Dry mouth
Haemorrhage (bleeding)
Iron deficiency anaemia
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Osteoporosis (bones weak and more likely to break)

60+:

Anaemia (lack of blood)
Compression fracture (fracture due to pressure caused by injury)
Plasma cell myeloma (cancer that begins in plasma cells)
Neoplasm malignant (cancer tumour)
Visual impairment
Confusional state
Pneumonia
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Albumin urine present
Angioedema (rapid swelling of the dermis)

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 9 people, 47.37%
Pain: 9 people, 47.37%
Dyspnea (difficult or laboured breathing): 8 people, 42.11%
Nausea (feeling of having an urge to vomit): 8 people, 42.11%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 42.11%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 6 people, 31.58%
Thalamic Infarction (tissue death of thalamus part of brain): 6 people, 31.58%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 5 people, 26.32%
Swelling: 5 people, 26.32%
Muscle Spasms (muscle contraction): 5 people, 26.32%

* Approximation only. Some reports may have incomplete information.

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