Ambien cr and Buspirone hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien cr (zolpidem tartrate) and Buspirone hcl (buspirone hydrochloride). Common drug interactions include nausea among females and brain oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien cr and Buspirone hcl. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien cr?

Ambien cr has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 5,660 Ambien cr users. Check the latest studies of Ambien cr.

What is Buspirone hcl?

Buspirone hcl has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,821 Buspirone hcl users. Check the latest studies of Buspirone hcl.

On Jul, 05, 2026

58 people who take Ambien cr and Buspirone hcl together, and have interactions are studied.

Ambien cr and Buspirone hcl drug interactions.

What are the common drug interactions of Ambien Cr and Buspirone Hcl, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Pain
Abnormal behaviour
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Diarrhoea
Headache (pain in head)
Injury
Obesity (having too much body fat)

male:

Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac hypertrophy (thickening of the heart muscle)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hyperglycaemia (high blood sugar)
Suicidal ideation
Type 2 diabetes mellitus
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Catatonia (unresponsive to external stimuli)

What are the common drug interactions of Ambien Cr and Buspirone Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac hypertrophy (thickening of the heart muscle)
Drug level increased
Pulmonary congestion (congestion in the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Splenomegaly (enlargement of spleen)
Urinary retention (the inability to completely or partially empty the bladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder
Injury

40-49:

Back disorder
Back pain
Cerebral infarction (less blood supply to brain resulting tissue damage)
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Emotional distress
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Herpes zoster
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Obesity (having too much body fat)
Concussion (short loss of normal brain function in response to a head injury)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fall
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hyperglycaemia (high blood sugar)
Loss of consciousness
Neuropathy peripheral (surface nerve damage)
Suicidal ideation
Type 2 diabetes mellitus

60+:

Feeling hot
Food craving
Nausea (feeling of having an urge to vomit)
Small intestinal obstruction (blockage in small intestine)
Therapeutic response unexpected

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 25 people, 43.10%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 21 people, 36.21%
Sleep Disorder: 7 people, 12.07%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 8.62%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.17%
Premenstrual Syndrome: 3 people, 5.17%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 5.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.17%
Depression: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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