Ambien cr and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien cr (zolpidem tartrate) and Pregabalin (pregabalin). Common drug interactions include alopecia among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien cr and Pregabalin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien cr?

Ambien cr has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 5,660 Ambien cr users. Check the latest studies of Ambien cr.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.



On Jul, 17, 2026

16 people who take Ambien cr and Pregabalin together, and have interactions are studied.

Ambien cr and Pregabalin drug interactions.

What are the common drug interactions of Ambien Cr and Pregabalin, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Dyspnoea (difficult or laboured respiration)
  3. Feeling cold
  4. Hot flush (sudden feelings of heat)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Ill-defined disorder
  7. Memory impairment
  8. Menopause (end of monthly cycles in women)
  9. Migraine (headache)
  10. Mood swings (an extreme or rapid change in mood)

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Ambien Cr and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Adnexa uteri pain
  3. Alopecia (absence of hair from areas of the body)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Back pain
  7. Depression
  8. Feeling cold
  9. Headache (pain in head)
  10. Hot flush (sudden feelings of heat)

50-59:

  1. Hypersensitivity

60+:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Alopecia (absence of hair from areas of the body)
  6. Anxiety
  7. Decreased appetite
  8. Depression
  9. Drug dependence
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Breast Cancer Female: 3 people, 18.75%
  2. Pain: 3 people, 18.75%
  3. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 12.50%
  4. Constipation: 2 people, 12.50%
  5. Dyshidrotic Eczema (skin condition in which blisters develop on the soles of your feet and/or the palms of hands): 2 people, 12.50%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  7. Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 12.50%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 12.50%
  9. Muscle Spasms (muscle contraction): 2 people, 12.50%
  10. Nausea (feeling of having an urge to vomit): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien cr and Pregabalin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ambien cr and Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien cr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pregabalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate and pregabalin (the active ingredients of Ambien cr and Pregabalin, respectively), and Ambien cr and Pregabalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: