Ambien and Chlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Chlorothiazide (chlorothiazide). Common drug interactions include pneumonia among females and hernia among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Chlorothiazide. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Chlorothiazide?

Chlorothiazide has active ingredients of chlorothiazide. eHealthMe is studying from 1,220 Chlorothiazide users. Check the latest studies of Chlorothiazide.

On Jul, 27, 2026

12 people who take Ambien and Chlorothiazide together, and have interactions are studied.

Ambien and Chlorothiazide drug interactions.

What are the common drug interactions of Ambien and Chlorothiazide, by gender? *:

female:

Pneumonia
Sinusitis (inflammation of sinus)
Abdominal discomfort
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)

male:

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Loss of consciousness
Nausea (feeling of having an urge to vomit)
Vomiting
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Tracheostomy infection (infection of trachea surgical opening)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Pneumonia
Arthropathy

What are the common drug interactions of Ambien and Chlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Loss of consciousness
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Tracheostomy infection (infection of trachea surgical opening)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Pneumonia

30-39:

n/a

40-49:

Dysuria (painful or difficult urination)

50-59:

n/a

60+:

Asthenia (weakness)
Malaise (a feeling of general discomfort or uneasiness)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Blood creatinine increased
Blood potassium increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Cellulitis (infection under the skin)
Diarrhoea

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 16.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Immunodeficiency Disorders: 1 person, 8.33%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 8.33%
Cardiac Failure Congestive: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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