Ambien and Coreg cr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Coreg cr (carvedilol phosphate). Common drug interactions include aortic occlusion among females and cardiac disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Ambien and Coreg cr. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.
What is Coreg cr?
Coreg cr has active ingredients of carvedilol phosphate. It is often used in high blood pressure. eHealthMe is studying from 1,628 Coreg cr users. Check the latest studies of Coreg cr.
14 people who take Ambien and Coreg cr together, and have interactions are studied.

What are the common drug interactions of Ambien and Coreg Cr, by gender? *:
female:
- Aortic occlusion
- Dyspnoea (difficult or laboured respiration)
- Stent placement
- Abasia (inability to walk)
- Arterial disorder
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Balance disorder
- Cardiac failure congestive
- Chest pain
- Decreased appetite
male:
- Cardiac disorder
- Dyspnoea (difficult or laboured respiration)
- Joint swelling
- Muscle atrophy (a decrease in the mass of the muscle)
- Drug ineffective
- Gout (uric acid crystals building up in the body)
- Multiple allergies (allergy to multiple agents)
- Muscle spasms (muscle contraction)
- Tinnitus (a ringing in the ears)
- Weight decreased
What are the common drug interactions of Ambien and Coreg Cr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Drug effect decreased
50-59:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pneumonia
- Visual impairment
- Blindness
- Drug ineffective
- Fall
- Hypoxia (low oxygen in tissues)
- Intraocular melanoma (cancer (melanoma) of the eye)
- Monoplegia (a paralysis of a single limb)
- Muscle spasms (muscle contraction)
60+:
- Drug ineffective
- Uterine pain
- Vulvovaginal dryness
What are the existing conditions these people have? *
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 21.43%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 21.43%
- Cardiac Failure Congestive: 2 people, 14.29%
- Sleep Disorder: 2 people, 14.29%
- Pericardial Effusion (fluid around the heart): 2 people, 14.29%
- Diarrhea: 2 people, 14.29%
- Lung Disorder (lung disease): 2 people, 14.29%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
- Constipation: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Ambien and Coreg cr?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ambien and Coreg cr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Coreg cr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg cr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on zolpidem tartrate and carvedilol phosphate (the active ingredients of Ambien and Coreg cr, respectively), and Ambien and Coreg cr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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