Promacta and Levothyroxine sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Levothyroxine sodium (levothyroxine sodium). Common drug interactions include joint swelling among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Promacta and Levothyroxine sodium. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

On Jul, 19, 2026

90 people who take Promacta and Levothyroxine sodium together, and have interactions are studied.

Promacta and Levothyroxine sodium drug interactions.

What are the common drug interactions of Promacta and Levothyroxine Sodium, by gender? *:

female:

Joint swelling
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Purpura (purplish discoloration of the skin)
Pyrexia (fever)

male:

Hypertension (high blood pressure)
Arthralgia (joint pain)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Ascites (accumulation of fluid in the abdominal cavity)
Chronic hepatic failure (long lasting liver failure)
Coagulopathy (blood's ability to clot is impaired)
Diarrhoea
Erythema of eyelid (redness of the eyelid)
Escherichia sepsis (bacterial infection by escherichia coli)

What are the common drug interactions of Promacta and Levothyroxine Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaemia (lack of blood)
Drug ineffective
Haemoglobin decreased
Haemorrhage (bleeding)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Platelet count decreased

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Chest pain
Fatigue (feeling of tiredness)
Platelet count increased
Pneumonia
Pyrexia (fever)
Renal vein thrombosis (blood clot in renal vein)
Thrombocytosis
Vaginal haemorrhage (vaginal bleeding)

50-59:

Enterovesical fistula
Erythema of eyelid (redness of the eyelid)
Fatigue (feeling of tiredness)
Haematemesis (vomiting of blood)
Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Papule
Photosensitivity reaction
Platelet count decreased

60+:

Pain in extremity
Death
Haemoglobin decreased
Oedema peripheral (superficial swelling)
Platelet count decreased
Abdominal pain
Cellulitis (infection under the skin)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 19 people, 21.11%
Multiple Myeloma (cancer of the plasma cells): 6 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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