Ambien and Tyvaso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Tyvaso (treprostinil sodium). Common drug interactions include throat irritation among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Tyvaso. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

On Jul, 08, 2026

83 people who take Ambien and Tyvaso together, and have interactions are studied.

What are the common drug interactions of Ambien and Tyvaso, by gender? *:

female:

Throat irritation
Fluid retention (an abnormal accumulation of fluid in the blood)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Constipation
Pulmonary oedema (fluid accumulation in the lungs)
Wheezing (a high-pitched whistling sound made while you breath)
Chest discomfort
Flushing (the warm, red condition of human skin)
Asthenia (weakness)
Death

male:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Constipation
Cough
Dehydration (dryness resulting from the removal of water)
Blood creatinine increased
Death
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Ambien and Tyvaso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abasia (inability to walk)
Arthralgia (joint pain)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Femur fracture
Pain in extremity
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Cardiac disorder

10-19:

n/a

20-29:

n/a

30-39:

Blood urine present
Diarrhoea
Eye inflammation
Fatigue (feeling of tiredness)
Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
Platelet count decreased
Weight decreased
White blood cell count decreased
Chest pain
Dyspnoea (difficult or laboured respiration)

40-49:

Dyspnoea exertional (breathlessness or shortness of breath)
Headache (pain in head)
Abdominal pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Crepitations (noises are produced by the rubbing of parts one against the other)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Lipase increased
Pancreatitis (inflammation of pancreas)

50-59:

Dizziness
Flushing (the warm, red condition of human skin)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Pain in jaw
Pneumonia
Throat irritation
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Trismus (reduced opening of the jaws)
Abdominal pain
Anion gap increased

60+:

Oedema peripheral (superficial swelling)
Diarrhoea
Acute respiratory failure
Dizziness
Malaise (a feeling of general discomfort or uneasiness)
Oedema (fluid collection in tissue)
Pneumonia
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 62 people, 74.70%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 24 people, 28.92%
Pain: 9 people, 10.84%

* Approximation only. Some reports may have incomplete information.

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