Amiodarone hydrochloride and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amiodarone hydrochloride (amiodarone hydrochloride) and Ibu (ibuprofen). Common drug interactions include gastrointestinal disorder among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Amiodarone hydrochloride and Ibu. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Amiodarone hydrochloride?

Amiodarone hydrochloride has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 10,061 Amiodarone hydrochloride users. Check the latest studies of Amiodarone hydrochloride.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.



On Jul, 30, 2026

88 people who take Amiodarone hydrochloride and Ibu together, and have interactions are studied.

Amiodarone hydrochloride and Ibu drug interactions.

What are the common drug interactions of Amiodarone Hydrochloride and Ibu, by gender? *:

female:

  1. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  2. Haemorrhage (bleeding)
  3. Implant site pain
  4. Patella fracture
  5. Pruritus (severe itching of the skin)
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  7. Skin atrophy (wasting of skin)
  8. Urinary tract disorder
  9. Weight decreased
  10. Abdominal distension

male:

  1. Diarrhoea
  2. Asthenia (weakness)
  3. Drug ineffective
  4. Fatigue (feeling of tiredness)
  5. Blood pressure increased
  6. Infection
  7. Pneumonia
  8. Renal failure (kidney dysfunction)
  9. Drug level increased
  10. Chronic kidney disease

What are the common drug interactions of Amiodarone Hydrochloride and Ibu, by age (0-1 to 60+)? *:

0-1:

  1. Acute circulatory failure (shock)
  2. Encephalopathy (functioning of the brain is affected by some agent or condition)
  3. Hepatic failure (liver failure)
  4. Multi-organ failure (multisystem organ failure)
  5. Renal failure acute (rapid kidney dysfunction)

2-9:

n/a

10-19:

  1. Cardiac arrest
  2. Completed suicide (act of taking one's own life)
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

20-29:

  1. Apnoea (suspension of external breathing)
  2. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  3. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  4. Oedema (fluid collection in tissue)
  5. Pulseless electrical activity
  6. Vomiting

30-39:

  1. Excessive bronchial secretion
  2. Hypotension (abnormally low blood pressure)
  3. Hypoxia (low oxygen in tissues)
  4. Atrioventricular block (heart block)
  5. Cardiac arrest

40-49:

  1. Electrocardiogram qt prolonged
  2. Asthenia (weakness)
  3. Blood pressure decreased
  4. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  5. Cardiac arrest
  6. Chest pain
  7. Drug hypersensitivity
  8. Drug level increased
  9. Electrocardiogram st segment elevation
  10. Electrocardiogram t wave biphasic

50-59:

  1. Myelosuppression (a decrease in the production of blood cells)
  2. Pneumonia
  3. Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

  1. Diarrhoea
  2. Asthenia (weakness)
  3. Fatigue (feeling of tiredness)
  4. Drug ineffective
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Blood creatinine increased
  7. Blood urea increased
  8. Chest pain
  9. Renal failure acute (rapid kidney dysfunction)
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. High Blood Pressure: 20 people, 22.73%
  2. Immunodeficiency Common Variable: 14 people, 15.91%
  3. Depression: 10 people, 11.36%
  4. Anaemia (lack of blood): 9 people, 10.23%
  5. Spinal Osteoarthritis (joint cartilage loss in spine): 8 people, 9.09%
  6. Urinary Tract Infection: 8 people, 9.09%
  7. Headache (pain in head): 8 people, 9.09%
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 7 people, 7.95%
  9. Hypersensitivity: 6 people, 6.82%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.68%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amiodarone hydrochloride and Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amiodarone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amiodarone hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibu and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride and ibuprofen (the active ingredients of Amiodarone hydrochloride and Ibu, respectively), and Amiodarone hydrochloride and Ibu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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