Amitiza and Methimazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitiza (lubiprostone) and Methimazole (methimazole). Common drug interactions include abdominal distension among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Amitiza and Methimazole. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

On Aug, 01, 2026

30 people who take Amitiza and Methimazole together, and have interactions are studied.

Amitiza and Methimazole drug interactions.

What are the common drug interactions of Amitiza and Methimazole, by gender? *:

female:

Abdominal distension
Abdominal pain
Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Deficiency anaemia
Diarrhoea
Dyspnoea at rest (difficult or laboured breathing during rest)
Dyspnoea exertional (breathlessness or shortness of breath)
Eating disorder
Haemorrhage (bleeding)

male:

Death
Cardiac failure congestive
Chronic kidney disease
Renal failure (kidney dysfunction)

What are the common drug interactions of Amitiza and Methimazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Chronic kidney disease
Hypokinesia (decreased bodily movement)
Hypotension (abnormally low blood pressure)
Loss of consciousness

60+:

Asthenia (weakness)
Dizziness
Blood potassium decreased
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Chronic kidney disease
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Pain of skin
White blood cell count decreased

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 10 people, 33.33%
Depression: 8 people, 26.67%
Thyroid Diseases: 8 people, 26.67%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 7 people, 23.33%
Blood Pressure Abnormal: 5 people, 16.67%
Breast Cancer: 5 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.33%
Urinary Tract Infection: 3 people, 10.00%
Bacterial Infection: 3 people, 10.00%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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