Amitriptyline hydrochloride and Cilostazol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amitriptyline hydrochloride (amitriptyline hydrochloride) and Cilostazol (cilostazol). Common drug interactions include myocardial infarction among females and dry skin among males.

The phase IV clinical study analyzes what interactions people have when they take Amitriptyline hydrochloride and Cilostazol. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.

What is Cilostazol?

Cilostazol has active ingredients of cilostazol. It is often used in arteriosclerosis of the extremities. eHealthMe is studying from 7,877 Cilostazol users. Check the latest studies of Cilostazol.



On Jul, 07, 2026

17 people who take Amitriptyline hydrochloride and Cilostazol together, and have interactions are studied.

Amitriptyline hydrochloride and Cilostazol drug interactions.

What are the common drug interactions of Amitriptyline Hydrochloride and Cilostazol, by gender? *:

female:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Necrosis (the death of body tissue)
  3. Oesophageal achalasia (difficulty swallowing, food sticking in the oesophagus)
  4. Osteoporosis (bones weak and more likely to break)
  5. Overdose
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
  8. Peripheral vascular disorder
  9. Pleural effusion (water on the lungs)
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

male:

  1. Dry skin
  2. Joint range of motion decreased (disease of joint movement)
  3. Pulmonary function test decreased
  4. Rash
  5. Rash papular (redness with papule)
  6. Skin disorder (skin disease)
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Skin fibrosis (fibrous tissue formation on skin)
  9. Skin hypertrophy (skin cells enlarges)
  10. Skin induration (an abnormally hard spot or area on the skin)

What are the common drug interactions of Amitriptyline Hydrochloride and Cilostazol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Headache (pain in head)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Pain
  4. Pain in extremity
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Dyskinesia (abnormality or impairment of voluntary movement)

50-59:

  1. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  2. Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)

60+:

  1. Pain
  2. Skin ulcer
  3. Oedema peripheral (superficial swelling)
  4. Peau d'orange (orange peel skin)
  5. Pigmentation disorder (disturbances of human skin colour)
  6. Pulmonary function test decreased
  7. Rash
  8. Rash papular (redness with papule)
  9. Skin disorder (skin disease)
  10. Skin exfoliation (removal of the oldest dead skin cells)

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 41.18%
  2. High Blood Cholesterol: 5 people, 29.41%
  3. Pain: 4 people, 23.53%
  4. Diabetes: 4 people, 23.53%
  5. Cardiac Failure Congestive: 2 people, 11.76%
  6. Depression: 2 people, 11.76%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
  8. Bleeding Disorders: 1 person, 5.88%
  9. Blockage Of Leg Arteries: 1 person, 5.88%
  10. Blood Glucose Abnormal: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Amitriptyline hydrochloride and Cilostazol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amitriptyline hydrochloride and Cilostazol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amitriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cilostazol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amitriptyline hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cilostazol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride and cilostazol (the active ingredients of Amitriptyline hydrochloride and Cilostazol, respectively), and Amitriptyline hydrochloride and Cilostazol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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