Amlodipine besylate and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine besylate (amlodipine besylate) and Zelnorm (tegaserod maleate). Common drug interactions include pyrexia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine besylate and Zelnorm. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine besylate?

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 75,293 Amlodipine besylate users. Check the latest studies of Amlodipine besylate.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

On Jul, 04, 2026

69 people who take Amlodipine besylate and Zelnorm together, and have interactions are studied.

Amlodipine besylate and Zelnorm drug interactions.

What are the common drug interactions of Amlodipine Besylate and Zelnorm, by gender? *:

female:

Pyrexia (fever)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sinusitis (inflammation of sinus)
Tinnitus (a ringing in the ears)
Troponin increased
Ventricular extrasystoles (premature cardiac contraction)
Vitamin b12 deficiency
Vitamin d deficiency
White blood cell count increased
Cardiac disorder

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Constipation
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Amlodipine Besylate and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Inflammatory bowel disease
Rectal ulcer (ulcer of rectum)
Constipation
Rectal abscess (pus in rectum)
Stress

30-39:

Atrioventricular block (heart block)
Blood chloride increased
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Bradycardia (abnormally slow heart action)
Hypotension (abnormally low blood pressure)
Troponin increased
White blood cell count increased
Cardiogenic shock (inadequate circulation of blood)
Mitral valve incompetence (inefficient heart valve)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Blindness
Blood glucose decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Deafness
Dry skin
Erythema (redness of the skin)
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)

50-59:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Bunion (a painful swelling on the first joint of the big toe)
Cellulitis (infection under the skin)
Cerumen impaction
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cystitis (inflammation of the wall of the bladder)
Depression
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pulmonary mass
Blood cholesterol increased
Dyspnoea (difficult or laboured respiration)
Pancreatic cyst
Chest pain
Renal failure (kidney dysfunction)
Constipation
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 28 people, 40.58%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 24 people, 34.78%
High Blood Cholesterol: 17 people, 24.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 24.64%
Pain: 14 people, 20.29%
Constipation: 12 people, 17.39%
Irritable Bowel Syndrome: 12 people, 17.39%
Infection: 10 people, 14.49%
Type 2 Diabetes: 8 people, 11.59%
Hypersensitivity: 8 people, 11.59%

* Approximation only. Some reports may have incomplete information.

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