Amlodipine and Capoten drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Capoten (captopril). Common drug interactions include cardiac arrest among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Capoten. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,830 Amlodipine users. Check the latest studies of Amlodipine.

What is Capoten?

Capoten has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 2,954 Capoten users. Check the latest studies of Capoten.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

68 people who take Amlodipine and Capoten together, and have interactions are studied.

Amlodipine and Capoten drug interactions.

What are the common drug interactions of Amlodipine and Capoten, by gender? *:

female:

Cardiac arrest
Cough
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Weight increased
Anaemia (lack of blood)
Arthralgia (joint pain)
Bilirubin conjugated increased
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Conjunctival haemorrhage (bleeding underneath the conjunctiva)

male:

Abdominal pain
Nausea (feeling of having an urge to vomit)
Cerebral atrophy (decrement in size of brain)
Diarrhoea
Haematemesis (vomiting of blood)
Proctalgia (pain in the rectum)
Pyrexia (fever)
Respiratory syncytial virus infection (viral disease of respiratory system)
Skin nodule (slightly elevated lesions on or in the skin)
Fatigue (feeling of tiredness)

What are the common drug interactions of Amlodipine and Capoten, by age (0-1 to 60+)? *:

0-1:

Blood creatinine decreased
Chronic kidney disease
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Persistent foetal circulation (baby's blood does not need to pass by the lungs)
Proteinuria (presence of protein in the urine)
Weight gain poor

2-9:

Abdominal pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Amaurosis (partial or total blindness without visible change in the eye)
Headache (pain in head)
Irritability
Vision blurred
Cerebral atrophy (decrement in size of brain)
Diarrhoea
Haematemesis (vomiting of blood)
Nausea (feeling of having an urge to vomit)

10-19:

n/a

20-29:

Coma (state of unconsciousness lasting more than six hours)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain
Abdominal pain upper
Bilirubin conjugated increased
Bradycardia (abnormally slow heart action)
Confusional state
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Cough

30-39:

n/a

40-49:

Abdominal pain
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Lymphoedema (localized fluid retention and tissue swelling)
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Pain in limb
Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
Vomiting
Chest pain

50-59:

Gout (uric acid crystals building up in the body)
Hypokalaemia (low potassium)
Intermittent claudication
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Abdominal discomfort
Actinomyces test positive
Anaphylactic reaction (serious allergic reaction)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)

60+:

Atrioventricular block first degree (heart block first degree)
Bradycardia (abnormally slow heart action)
Cataract (clouding of the lens inside the eye)
Chronic kidney disease
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)

What are the existing conditions these people have? *

Diabetes: 8 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 10.29%
Headache (pain in head): 5 people, 7.35%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 5.88%
Pain: 4 people, 5.88%
Cardiac Disorder: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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