Amlodipine and Malic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Malic acid (alpha hydroxy acids). Common drug interactions include somnolence among females and cardiogenic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Malic acid. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,830 Amlodipine users. Check the latest studies of Amlodipine.

What is Malic acid?

Malic acid has active ingredients of alpha hydroxy acids. It is often used in fibromyalgia. eHealthMe is studying from 246 Malic acid users. Check the latest studies of Malic acid.

On Aug, 02, 2026

40 people who take Amlodipine and Malic acid together, and have interactions are studied.

Amlodipine and Malic acid drug interactions.

What are the common drug interactions of Amlodipine and Malic Acid, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Nerve injury
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Drug ineffective
Anaphylactic reaction (serious allergic reaction)
Anxiety
Hirsutism (abnormal growth of hair on a person's face and body, esp. on a woman)

male:

Cardiogenic shock (inadequate circulation of blood)
Cardiomyopathy (weakening of the heart muscle)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Amlodipine and Malic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Nerve compression
Neuralgia (pain in one or more nerves)
Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Nerve injury
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Drug ineffective

50-59:

n/a

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Renal failure (kidney dysfunction)
Cardiogenic shock (inadequate circulation of blood)
Cardiomyopathy (weakening of the heart muscle)
Headache (pain in head)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Oropharyngeal pain

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 34 people, 85.00%
Drowsiness: 4 people, 10.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 10.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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