Amlodipine and Ozurdex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Ozurdex (dexamethasone). Common drug interactions include endophthalmitis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Ozurdex. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Ozurdex?

Ozurdex has active ingredients of dexamethasone. eHealthMe is studying from 2,497 Ozurdex users. Check the latest studies of Ozurdex.



On Jul, 03, 2026

43 people who take Amlodipine and Ozurdex together, and have interactions are studied.

Amlodipine and Ozurdex drug interactions.

What are the common drug interactions of Amlodipine and Ozurdex, by gender? *:

female:

  1. Endophthalmitis (inflammation of the internal coats of the eye)
  2. Eye pain
  3. Visual impairment
  4. Abdominal pain
  5. Diarrhoea
  6. Hypopyon (pus in the eye)
  7. Intervertebral disc operation
  8. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  9. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  10. Procedural pain

male:

  1. Asthenia (weakness)
  2. Nausea (feeling of having an urge to vomit)
  3. Vitreous haemorrhage (intraocular (inside the eye) bleeding)
  4. Device dislocation
  5. Acute myocardial infarction (acute heart attack)
  6. Blepharitis (chronic inflammation of the eyelid)
  7. Complication of device insertion
  8. Corneal oedema (corneal swelling)
  9. Eye pruritus (eye itching)
  10. Insomnia (sleeplessness)

What are the common drug interactions of Amlodipine and Ozurdex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Insomnia (sleeplessness)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Stress

50-59:

  1. Asthenia (weakness)
  2. Nausea (feeling of having an urge to vomit)
  3. Sinus node dysfunction (a group of abnormal heart rhythms)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Device dislocation

60+:

  1. Endophthalmitis (inflammation of the internal coats of the eye)
  2. Visual impairment
  3. Corneal deposits
  4. Drug ineffective
  5. Eye pruritus (eye itching)
  6. Hypopyon (pus in the eye)
  7. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  8. Ocular hypertension (intraocular pressure higher than normal)
  9. Post procedural infection
  10. Retinal degeneration (death of the cells of the retina)

What are the existing conditions these people have? *

  1. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 8 people, 18.60%
  2. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 8 people, 18.60%
  3. Diabetes: 7 people, 16.28%
  4. Retinal Vessel Occlusion (a blockage in one of the small arteries): 3 people, 6.98%
  5. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amlodipine and Ozurdex:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ozurdex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amlodipine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ozurdex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and dexamethasone (the active ingredients of Amlodipine and Ozurdex, respectively), and Amlodipine and Ozurdex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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